Understanding the fundamental properties and safety considerations of chemical compounds is paramount for their effective and safe use in any setting. This article, presented by NINGBO INNO PHARMCHEM CO.,LTD., focuses on 1-chlorobutane (CAS 109-69-3), detailing its key chemical and physical characteristics, along with essential safety and handling guidelines.

1-Chlorobutane, also known as n-butyl chloride, is classified as a highly flammable liquid. Its appearance is typically that of a clear, colorless liquid, accompanied by a pungent odor. Key physical properties include a boiling point of approximately 77-78°C and a melting point of -123°C. With a density of around 0.886 g/mL at 25°C, it is less dense than water, a property that can be relevant in certain separation processes.

From a chemical standpoint, 1-chlorobutane is an alkyl halide. It exhibits moderate reactivity, making it a useful butylation reagent in organic synthesis. However, its flammability poses the most significant safety concern. The compound has a low flash point of -12°C, meaning it can easily ignite in the presence of an ignition source. Its vapor can form explosive mixtures with air, with explosive limits typically ranging from 1.8% to 10.1% by volume.

Due to these hazardous properties, stringent safety protocols must be followed when handling 1-chlorobutane. It should always be stored in a cool, well-ventilated area, away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents and strong bases. Containers must be kept tightly closed to prevent the escape of flammable vapors. In industrial settings, grounding and bonding of equipment used for transferring larger quantities are crucial to prevent the buildup of static electricity, which could act as an ignition source.

Personal protective equipment (PPE) is essential when working with 1-chlorobutane. This includes chemical-resistant gloves (such as nitrile or neoprene), safety goggles or a face shield to protect the eyes, and appropriate respiratory protection if ventilation is inadequate. In case of spills, immediate containment and absorption with an inert material are necessary, followed by proper disposal according to local regulations. It is critical to prevent the release of 1-chlorobutane into the environment, as it can be harmful to aquatic life.

NINGBO INNO PHARMCHEM CO.,LTD. prioritizes safety and quality in the supply of 1-chlorobutane. We provide comprehensive safety data sheets (SDS) with detailed information on hazards, handling, and emergency procedures. Adherence to these guidelines ensures the safe and efficient utilization of 1-chlorobutane in both laboratory and industrial environments.