Understanding the chemical nuances of specialized compounds is fundamental to harnessing their full potential. NINGBO INNO PHARMCHEM CO.,LTD. provides insights into the structure-activity relationships of important chemical intermediates like 2-(Cyclopropylamino)-4,6-diamino-5-pyrimidinecarbonitrile (CAS 112636-83-6).

The core structure of 2-(Cyclopropylamino)-4,6-diamino-5-pyrimidinecarbonitrile is a pyrimidine ring, a six-membered heterocyclic aromatic ring containing two nitrogen atoms. This foundational structure is adorned with specific functional groups that dictate its chemical behavior and applications. At the 4 and 6 positions, it features amino (-NH₂) groups, which are electron-donating and nucleophilic, contributing to its reactivity in various synthetic transformations. The presence of a cyano (-CN) group at the 5-position is a significant feature; it is an electron-withdrawing group that influences the electron distribution across the ring and can participate in diverse reactions, including nucleophilic additions and cycloadditions. A cyclopropylamino group is attached at the 2-position, adding a degree of steric bulk and unique electronic effects.

When compared to other pyrimidine derivatives, the specific arrangement of these functional groups in 2-(Cyclopropylamino)-4,6-diamino-5-pyrimidinecarbonitrile leads to distinct properties. For instance, compounds with different substituents at these positions might exhibit altered solubility, thermal stability, or photophysical characteristics. For example, derivatives with extended conjugated systems, like carbazole groups, might show enhanced luminescence, making them suitable for OLED applications, whereas compounds with halogen or azido groups can display heightened reactivity but potentially reduced stability. The cyclopropylamino moiety in our target compound is particularly interesting for its potential to influence biological activity, as seen in its applications as a pesticide intermediate.

The chemical reactivity of 2-(Cyclopropylamino)-4,6-diamino-5-pyrimidinecarbonitrile is largely governed by its functional groups. The amino groups can readily undergo acylation or alkylation reactions, while the cyano group can be hydrolyzed or reduced. These reactions allow chemists to further elaborate the molecule, creating a diverse library of derivatives with tailored properties for specific applications. As a trusted supplier, NINGBO INNO PHARMCHEM CO.,LTD. ensures that researchers and manufacturers have access to high-purity intermediates like this pyrimidine carbonitrile, facilitating the exploration of novel chemical space and the development of advanced materials and bioactive compounds.