In the intricate world of organic chemistry, certain compounds stand out due to their versatility and indispensable nature in synthetic processes. 2-Bromobenzamide, identified by its CAS number 4001-73-4, is precisely one such molecule. As a leading supplier of high-quality chemical intermediates, Ningbo Inno Pharmchem Co., Ltd. recognizes the significant impact of 2-Bromobenzamide on various research and industrial applications. This article delves into its properties, synthesis, and, most importantly, its wide-ranging applications.

Understanding 2-Bromobenzamide

2-Bromobenzamide, with the molecular formula C7H6BrNO and a molecular weight of approximately 200.03 g/mol, is a white to beige crystalline powder. Its structure, featuring a bromine atom ortho to the amide group on a benzene ring, imbues it with unique reactivity. This specific arrangement allows for targeted chemical modifications, making it a highly sought-after intermediate. Its melting point typically ranges from 160-162°C, indicating its solid state under standard conditions. The purity of 2-Bromobenzamide is often a critical factor for its use in sensitive synthetic pathways, with suppliers commonly offering grades of 97% or higher.

Key Synthesis Pathways and Applications

The synthesis of 2-Bromobenzamide is a well-established process, and its utility in subsequent reactions is extensive. One of its primary applications lies in the field of pharmaceutical intermediates. Researchers and chemical manufacturers utilize 2-Bromobenzamide in the development of various drug candidates. For instance, it has been employed in the microwave-assisted one-pot synthesis of substituted 3-(phenylmethylene)isoindolin-1-ones. This method offers a streamlined approach to complex heterocyclic compounds, which are often found in biologically active molecules.

Furthermore, the compound is instrumental in palladium-catalyzed synthesis reactions. These sophisticated catalytic processes are crucial for forming carbon-carbon and carbon-heteroatom bonds, essential for building complex molecular architectures. Specifically, 2-Bromobenzamide has been used in the synthesis of phenanthridinones, a class of fused heterocyclic compounds known for their potential therapeutic properties. The ability to efficiently construct such ring systems underscores the importance of high-purity 2-Bromobenzamide in enabling advanced organic synthesis.

Beyond pharmaceutical applications, 2-Bromobenzamide also finds its place in the development of novel materials and ligands. Its use in the synthesis of new water-soluble iminophosphorane ligands demonstrates its versatility in coordination chemistry and catalysis. These ligands can be critical components in developing new catalytic systems for various industrial processes. The demand for such specialized chemicals highlights the continuous innovation within the fine chemical sector, where intermediates like 2-Bromobenzamide play a pivotal role.

Sourcing and Quality Assurance

For researchers and manufacturers seeking reliable supplies of 2-Bromobenzamide, partnering with reputable chemical suppliers is paramount. Companies like Ningbo Inno Pharmchem Co., Ltd. are dedicated to providing high-purity intermediates, ensuring that experimental results are consistent and scalable. The availability of competitive pricing for 2-Bromobenzamide and the assurance of quality control are vital considerations for any project. When searching for 'buy 2-Bromobenzamide online' or '2-Bromobenzamide suppliers', it is important to verify the product specifications and the supplier's commitment to quality.

In conclusion, 2-Bromobenzamide (CAS 4001-73-4) is far more than just a chemical compound; it is an enabler of innovation in organic synthesis. Its diverse applications in pharmaceuticals, material science, and catalysis make it an indispensable tool for chemists worldwide. Ningbo Inno Pharmchem Co., Ltd. remains committed to supplying this essential intermediate, supporting the scientific community in its pursuit of new discoveries and advanced chemical solutions.