In the dynamic field of pharmaceutical development, the availability of high-quality intermediates is paramount. 2-Bromo-3-methyl-5-chloropyridine, identified by its CAS number 65550-77-8, stands out as a pivotal compound. Its unique structure, featuring a pyridine core with strategically placed bromine, chlorine, and methyl groups, renders it exceptionally useful for chemists aiming to construct complex molecular architectures. This article delves into the properties and applications of this vital pharmaceutical intermediate, highlighting why it is a sought-after building block for next-generation medicines.

The chemical and physical characteristics of 2-Bromo-3-methyl-5-chloropyridine are key to its efficacy. Typically appearing as an off-white to pale yellow crystalline solid, it possesses a melting point of 40-44°C. Its molecular formula, C6H5BrClN, and molecular weight of 206.468 g/mol underscore its precise composition. The presence of halogen atoms, bromine and chlorine, attached to the pyridine ring significantly enhances its reactivity. This makes it an ideal candidate for a variety of cross-coupling reactions, such as Suzuki-Miyaura coupling and Buchwald-Hartwig amination, which are fundamental in forging new carbon-carbon and carbon-nitrogen bonds. The methyl group at the 3-position further influences its electronic profile, allowing for nuanced control over reaction pathways.

The primary application of 2-Bromo-3-methyl-5-chloropyridine lies in its role as an organic synthesis intermediate. Pharmaceutical chemists utilize it extensively to synthesize Active Pharmaceutical Ingredients (APIs). The pyridine scaffold is a common feature in many therapeutic agents, and this compound provides a readily functionalized entry point into such structures. It is instrumental in the development of drugs targeting a wide spectrum of diseases, from neurological disorders to infectious agents. The ability to efficiently introduce the substituted pyridine moiety into larger molecules streamlines the drug discovery and development process, ultimately leading to faster market entry for new treatments. When searching for a reliable CAS 65550-77-8 supplier, prioritizing quality and consistency is crucial for these demanding applications.

Beyond pharmaceuticals, 2-Bromo-3-methyl-5-chloropyridine also finds significant use in the agrochemical industry. It serves as a precursor for synthesizing various pesticides and herbicides. The tailored design of these agrochemicals, often incorporating pyridine structures, helps protect crops from pests and diseases, thereby improving agricultural productivity and food security. The compound’s versatile reactivity allows for the creation of molecules with specific biological activities tailored for crop protection. For industries looking to buy 2-Bromo-3-methyl-5-chloropyridine, partnering with a reputable 2-Bromo-3-methyl-5-chloropyridine manufacturer in China ensures access to high-purity material essential for these applications.

Proper storage and handling of 2-Bromo-3-methyl-5-chloropyridine are vital to maintain its integrity. It is recommended to store it in a cool, well-ventilated area, away from incompatible substances. Typically packaged in 25 kg drums, it can also be supplied in custom quantities to meet diverse client needs, from laboratory-scale research to industrial production. The high assay purity, often exceeding 98.0%, underscores the quality assurance provided by leading manufacturers. This focus on quality is a key differentiator for any 2-Bromo-3-methyl-5-chloropyridine supplier aiming to serve the stringent demands of the pharmaceutical and agrochemical sectors.

In conclusion, 2-Bromo-3-methyl-5-chloropyridine is a cornerstone of modern chemical synthesis. Its utility as a versatile organic synthesis intermediate, combined with its critical role in developing life-saving pharmaceuticals and essential agrochemicals, makes it an indispensable compound. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated manufacturer and supplier, committed to providing high-quality chemical intermediates that drive innovation across industries. We invite researchers and manufacturers to explore the potential of this compound for their groundbreaking projects.