Understanding the inherent properties and reactivity of chemical compounds is fundamental to their effective application. NINGBO INNO PHARMCHEM CO.,LTD. delves into the science behind 1-Bromoheptane (CAS 629-04-9), exploring its characteristics and chemical behavior that make it a valuable asset in organic synthesis.

Physicochemical Properties of 1-Bromoheptane

1-Bromoheptane, also known as n-heptyl bromide, presents as a clear, colorless to slightly yellow liquid. Its molecular formula, C7H15Br, indicates a seven-carbon saturated chain with a bromine atom at the terminal position. This structure dictates many of its properties. With a molecular weight of 179.1 g/mol, it exhibits a relatively low melting point of -58°C, ensuring it remains liquid even in moderately cold conditions. Its boiling point is around 180°C, making it manageable for standard laboratory distillations and reactions. The density is approximately 1.14 g/mL at 25°C, and its refractive index is typically around 1.4499. These properties are crucial for identifying and quantifying the compound during synthesis and analysis. The high purity, often stated as ≥99%, minimizes interference from other substances in reactions.

Reactivity in Organic Synthesis

The chemical reactivity of 1-Bromoheptane is primarily dictated by the carbon-bromine bond. Bromine is a good leaving group, making the carbon atom to which it is attached electrophilic and susceptible to nucleophilic attack. This characteristic underpins its extensive use in nucleophilic substitution reactions (SN1 and SN2). For instance, reacting 1-Bromoheptane with a nucleophile like cyanide ion (CN-) yields heptanenitrile, a precursor that can be further transformed into carboxylic acids or amines. Similarly, it readily undergoes reactions with organometallic reagents, such as Grignard reagents, to form new carbon-carbon bonds, extending carbon chains or building more complex structures. These reactions are foundational for many organic synthesis strategies. When chemists investigate 'heptyl bromide uses,' they are often exploring these reactivity patterns.

Safety and Handling Insights

As with many organic chemicals, 1-Bromoheptane has specific safety considerations. It is classified as a flammable liquid with a flash point of 141°F (60.5°C), necessitating storage and handling away from ignition sources. It is also incompatible with strong oxidizing agents and strong bases, which can lead to vigorous or hazardous reactions. Understanding these incompatibilities is vital when planning synthesis sequences. For those looking to buy 1-bromoheptane, consulting the Safety Data Sheet (SDS) provided by NINGBO INNO PHARMCHEM CO.,LTD. is essential for safe and effective utilization.

In essence, the physicochemical properties and predictable reactivity of 1-Bromoheptane make it an indispensable tool for chemists. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing this vital intermediate with the highest purity and comprehensive support for its safe and effective application in your synthesis projects.