3-Bromo-5-nitrobenzoic acid (CAS 6307-83-1) is a chemical compound that plays a significant role in various scientific disciplines, particularly in organic synthesis and pharmaceutical research. Understanding its properties, synthesis, and applications is crucial for researchers and chemists looking to leverage its potential. As a key intermediate, this compound offers a unique set of characteristics that make it valuable for creating more complex molecular structures.

Physically, 3-Bromo-5-nitrobenzoic acid typically appears as a light yellow crystal. Its molecular formula is C7H4BrNO4, with a molecular weight of approximately 246.015 g/mol. Key physical properties include a melting point in the range of 159-161°C and a density of about 1.892 g/cm³. Chemically, the presence of the bromine atom and the nitro group imparts strong electron-withdrawing characteristics to the molecule. This influences its reactivity, making it amenable to a variety of chemical transformations, including nucleophilic aromatic substitution and various coupling reactions at the bromine site.

The synthesis of 3-Bromo-5-nitrobenzoic acid is a subject of interest for chemical manufacturers and researchers alike. One common method involves the electrophilic bromination of 5-nitrobenzoic acid, typically using N-bromosuccinimide (NBS) in the presence of an acid catalyst. Another route involves the diazotization of 3-amino-5-nitrobenzoic acid followed by a Sandmeyer reaction with a bromide source. Ensuring high purity and yield is critical for its downstream applications. NINGBO INNO PHARMCHEM CO.,LTD. focuses on optimizing these synthesis processes to provide a reliable supply of this essential chemical.

The applications of 3-Bromo-5-nitrobenzoic acid are extensive. In organic synthesis, it serves as a versatile intermediate for the preparation of a wide array of compounds. Its structure is particularly useful in the synthesis of pharmaceutical intermediates, where it can be elaborated into molecules with potential therapeutic activity, such as those being investigated for antitubercular or anticancer properties. The ability to purchase high-quality 3-Bromo-5-nitrobenzoic acid from a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. is vital for consistent experimental results.

Furthermore, this compound finds application in the agrochemical industry as a precursor for herbicides and other crop protection agents. Its specific chemical structure can contribute to the biological efficacy of these agricultural products. In analytical chemistry, it is used as a derivatizing reagent to facilitate the detection and quantification of substances that are otherwise difficult to analyze. Its strong chromophore allows for enhanced sensitivity in techniques like HPLC. For businesses looking to source this compound, NINGBO INNO PHARMCHEM CO.,LTD. offers it as a competitively priced product from a trusted manufacturer, supporting diverse research and industrial needs.