In the chemical industry, a robust understanding of compound toxicology and carcinogenicity is not merely a regulatory requirement but a fundamental aspect of responsible operation. 4-Vinyl-1-cyclohexene (CAS 100-40-3) is a compound widely used for its industrial utility, but it also carries notable health hazards that necessitate stringent safety protocols. This article focuses on the toxicological profile and the evidence for carcinogenicity associated with 4-Vinyl-1-cyclohexene, providing critical information for safe handling and usage. Information from manufacturers and suppliers, such as NINGBO INNO PHARMCHEM CO.,LTD., is crucial for disseminating these safety insights. Understanding the 4-vinyl-1-cyclohexene safety data is paramount for any user, influencing how and where the chemical can be used and the precautions required during its purchase and handling.

Scientific research has classified 4-Vinyl-1-cyclohexene as a Group 2B carcinogen by the International Agency for Research on Cancer (IARC). This classification indicates that the compound is possibly carcinogenic to humans, based on sufficient evidence in experimental animals but limited or inadequate evidence in humans. Studies have indicated that exposure to 4-Vinyl-1-cyclohexene can lead to various adverse health effects. Beyond its carcinogenic potential, the compound is also noted for its reproductive toxicity, particularly its diepoxide metabolite, which can affect ovarian function. This raises concerns about potential impacts on fertility and reproductive health for exposed individuals.

Furthermore, 4-Vinyl-1-cyclohexene is a highly flammable liquid. Its vapors can form explosive mixtures with air, and it can react vigorously with oxidizing agents, creating fire and explosion hazards. The GHS hazard statements highlight these risks, including 'Highly Flammable liquid and vapour' (H225), 'May be fatal if swallowed and enters airways' (H304), and 'Causes skin irritation' (H315). The precautionary statements mandate strict measures such as keeping it away from heat and sparks, obtaining special instructions before use, and ensuring proper ventilation. The potential for damage to fertility or the unborn child (H361) further underscores the need for comprehensive safety awareness.

The implications of these toxicological and carcinogenic properties extend to occupational safety and environmental protection. Workers handling 4-Vinyl-1-cyclohexene must be properly trained in its safe handling, use appropriate personal protective equipment (PPE), including chemical-resistant gloves, eye protection, and respiratory protection when necessary. Storage areas should be designed to mitigate fire risks and prevent environmental release. The directive to avoid release to the environment (P273) is crucial, given its classification as harmful to aquatic life with long-lasting effects (H412).

For businesses involved in the 4-vinyl-1-cyclohexene manufacturing or its downstream use, a thorough risk assessment is essential. This includes evaluating potential exposure pathways, implementing engineering controls, and establishing emergency procedures. The availability of detailed safety data sheets (SDS) from suppliers like NINGBO INNO PHARMCHEM CO.,LTD. is critical for informing these safety assessments and ensuring regulatory compliance. By prioritizing safety and adhering to best practices, the industrial utility of 4-Vinyl-1-cyclohexene can be harnessed responsibly, minimizing risks to human health and the environment.