Understanding 1,3-Dibromo-5-fluorobenzene: Properties, Synthesis, and Market Availability
1,3-Dibromo-5-fluorobenzene (CAS 1435-51-4) is a vital aromatic compound that serves as a critical intermediate in various chemical processes, most notably in the synthesis of pharmaceuticals and advanced materials. NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing high-quality chemical building blocks, including this important dibrominated fluorobenzene derivative. Understanding its fundamental properties and synthesis is key for chemists and procurement specialists.
Chemically, 1,3-Dibromo-5-fluorobenzene is characterized by its distinct structure: a benzene ring with bromine atoms at the meta positions (1 and 3) and a fluorine atom at the other meta position (5). This arrangement makes it highly reactive in various cross-coupling reactions, such as Suzuki, Stille, and Heck couplings, enabling the formation of complex carbon-carbon bonds. The presence of fluorine often imparts desirable properties like increased lipophilicity and metabolic stability, making it a preferred choice for the development of novel drug candidates. This is why many seek to buy 1,3-Dibromo-5-fluorobenzene for their research and development needs.
The synthesis of 1,3-Dibromo-5-fluorobenzene typically involves electrophilic aromatic substitution reactions. Common routes might start from simpler fluorinated or brominated aromatic precursors. The ability to efficiently produce this compound in high purity is a hallmark of a capable 1,3-Dibromo-5-fluorobenzene manufacturer. For businesses looking to secure a consistent supply, identifying reputable 1,3-Dibromo-5-fluorobenzene suppliers that can guarantee product quality and timely delivery is paramount.
The market availability and the associated 1,3-Dibromo-5-fluorobenzene price are influenced by factors such as production scale, purity requirements, and global demand. As a key pharmaceutical intermediate, its demand often correlates with the pipeline of new drug development. NINGBO INNO PHARMCHEM CO.,LTD. endeavors to provide competitive pricing for this essential compound, ensuring accessibility for a wide range of scientific and industrial applications. The company’s commitment to quality makes it a trusted source for this critical aryl halogenated building block.
In summary, 1,3-Dibromo-5-fluorobenzene is an indispensable compound in modern chemistry. Its well-defined properties and versatile reactivity make it a sought-after intermediate for creating advanced molecules. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying this vital chemical, supporting innovation in pharmaceutical research and fine chemical synthesis.
Perspectives & Insights
Alpha Spark Labs
“Understanding its fundamental properties and synthesis is key for chemists and procurement specialists.”
Future Pioneer 88
“Chemically, 1,3-Dibromo-5-fluorobenzene is characterized by its distinct structure: a benzene ring with bromine atoms at the meta positions (1 and 3) and a fluorine atom at the other meta position (5).”
Core Explorer Pro
“This arrangement makes it highly reactive in various cross-coupling reactions, such as Suzuki, Stille, and Heck couplings, enabling the formation of complex carbon-carbon bonds.”