For chemists and researchers, a thorough understanding of a compound's chemical properties and synthesis routes is fundamental to its effective utilization. 3-Acetylpyridine, identified by its CAS number 350-03-8, is an organic compound that offers a fascinating study in chemical reactivity and synthesis. Its molecular formula, C7H7NO, and molecular weight of 121.14 g/mol, hint at its relatively simple yet versatile structure. Typically appearing as a clear, colorless to pale yellow liquid, it possesses a distinctive nutty odor, which is important for its application in flavors and fragrances.

The chemical properties of 3-Acetylpyridine are characteristic of both ketones and pyridines. The carbonyl group makes it susceptible to nucleophilic attack, while the pyridine ring can undergo electrophilic aromatic substitution, albeit with regioselectivity influenced by the acetyl group. Its melting point is between 11-13°C, and its boiling point is around 218-220°C. Solubility in common organic solvents like ethanol and chloroform, along with limited water solubility, dictates its use in various reaction media and formulations. For those looking to buy 3-Acetylpyridine online, understanding these properties is key to successful application.

The synthesis of 3-Acetylpyridine can be achieved through several methods, often involving the condensation of pyridine derivatives with acetylating agents. One common approach involves the reaction of ethyl nicotinate with ethyl acetoacetate, followed by hydrolysis. Another method described in literature includes the preparation from nicotinic acid and calcium acetate. The efficiency and purity of the synthesis route are crucial for producing high-grade material. NINGBO INNO PHARMCHEM CO.,LTD., as a leading acetylpyridine chemical supplier, ensures optimized synthesis processes to deliver a product that meets strict quality standards.

Handling 3-Acetylpyridine requires adherence to safety protocols. It is classified as a flammable liquid and can be irritating to the skin and eyes. Proper ventilation and personal protective equipment are essential when working with this compound. For researchers and manufacturers, sourcing from a reputable 3-Acetylpyridine supplier like NINGBO INNO PHARMCHEM CO.,LTD. not only guarantees quality but also provides access to necessary technical information and safety data, ensuring responsible use of this valuable chemical. Understanding the CAS 350-03-8 chemical properties and synthesis is the first step towards unlocking its full potential.