A deep understanding of a chemical compound's properties is fundamental to its successful application in various scientific and industrial processes. NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing detailed information and high-quality supply of critical chemical intermediates, such as 4-(Trifluoromethoxy)benzenesulfonamide (CAS: 1513-45-7). This article delves into the essential chemical and physical properties of this important organic synthesis intermediate.

4-(Trifluoromethoxy)benzenesulfonamide presents itself as a white solid, a form that simplifies handling and storage. Its physical characteristics are key indicators of its stability and behavior during chemical reactions. The compound exhibits a density of 1.519 g/cm³, suggesting a relatively compact molecular structure. Its melting point, which falls within the range of 146-148ºC, indicates a good degree of thermal stability under moderate conditions. This elevated melting point is beneficial for reactions that require heating, as it helps maintain the integrity of the molecule.

Further insights into its thermal behavior are provided by its boiling point of approximately 301.8ºC and a flash point of 136.3ºC. These parameters are crucial for safety assessments and for designing appropriate reaction conditions, especially when dealing with potentially exothermic processes or elevated temperatures. The refractive index, measured at 1.49, offers information about how light interacts with the compound, which can be useful in analytical methods for characterization and purity assessment.

The molecular formula of 4-(Trifluoromethoxy)benzenesulfonamide is C7H6F3NO3S, with a molecular weight of 241.18800. The presence of the trifluoromethoxy group (-OCF3) is a significant feature, known to increase lipophilicity and metabolic stability in organic molecules. Coupled with the sulfonamide group (-SO2NH2), which is a common pharmacophore and reactive site, this compound becomes a highly versatile building block for organic synthesis. Its utility spans across pharmaceutical research, agrochemical development, and material science, where these inherent properties can be leveraged to create molecules with specific desired functionalities.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to ensuring that the 4-(Trifluoromethoxy)benzenesulfonamide we supply adheres to strict quality specifications, typically an assay of ≥98.0% and a moisture content of ≤0.2%. These specifications are vital for guaranteeing the compound's effectiveness and reproducibility in synthesis. By providing reliable access to this compound with thoroughly documented properties, we empower researchers and industrial chemists to achieve their synthesis goals efficiently and effectively.