Understanding the Properties and Synthesis of 3,5-Dimethylanisole (CAS 874-63-5)
3,5-Dimethylanisole, identified by CAS number 874-63-5, is an organic compound that holds significant importance as an intermediate in various chemical processes. Understanding its inherent properties and how it is synthesized is fundamental for chemists, researchers, and manufacturers who utilize it in their work. This article aims to provide a comprehensive overview of these aspects, shedding light on why this aromatic ether is a valued component in the chemical industry.
The physical properties of 3,5-Dimethylanisole are key to its handling and application. It is typically described as a clear, colorless to light yellow liquid. Its molecular formula is C9H12O, and it has a molecular weight of approximately 136.19 g/mol. The compound exhibits a boiling point in the range of 193-194.5 °C and a melting point of -0.2 °C, indicating it is liquid at room temperature. Its flash point, around 65.6 °C, classifies it as a combustible liquid, requiring appropriate safety precautions during handling and storage.
Chemically, 3,5-Dimethylanisole is an aromatic ether. The benzene ring is substituted with a methoxy group (-OCH3) and two methyl groups (-CH3) at the 3 and 5 positions. This arrangement of substituents influences its reactivity. The electron-donating nature of both the methoxy and methyl groups activates the aromatic ring towards electrophilic substitution reactions. This makes it a versatile precursor for synthesizing more complex molecules. Its stability under normal conditions, while being reactive under specific chemical environments, makes it an ideal intermediate for 'organic synthesis building blocks' and 'chemical research reagents'.
The synthesis of 3,5-Dimethylanisole is most commonly achieved through the methylation of 3,5-dimethylphenol. This process involves reacting the phenol with a methylating agent, such as dimethyl sulfate or methyl iodide, typically in the presence of a base like potassium carbonate and often under reflux conditions. This method of '3,5-dimethylanisole synthesis' is favored for its efficiency and scalability, making it suitable for industrial production. The purity of the starting materials and the control of reaction parameters are crucial for obtaining a high yield of the desired product.
For manufacturers and researchers, securing a reliable source of high-quality 3,5-Dimethylanisole is essential. Reputable suppliers ensure that the synthesis processes are optimized for purity and consistency, providing detailed specifications and certificates of analysis. NINGBO INNO PHARMCHEM CO.,LTD., as a supplier in China, plays a vital role in making this compound accessible to the global market, supporting its wide-ranging applications from laboratory research to industrial manufacturing. The commitment to quality in its 'fine chemical intermediates' ensures that users can depend on its performance.
In summary, the physical and chemical properties of 3,5-Dimethylanisole, coupled with its accessible synthesis, establish it as a key compound in the chemical industry. Its utility as an intermediate and research reagent underscores its continued importance in driving innovation and scientific discovery.
Perspectives & Insights
Quantum Pioneer 24
“6 °C, classifies it as a combustible liquid, requiring appropriate safety precautions during handling and storage.”
Bio Explorer X
“The benzene ring is substituted with a methoxy group (-OCH3) and two methyl groups (-CH3) at the 3 and 5 positions.”
Nano Catalyst AI
“The electron-donating nature of both the methoxy and methyl groups activates the aromatic ring towards electrophilic substitution reactions.”