Understanding the Chemical Profile: Properties and Uses of 4-Bromo-2-fluorobenzoic Acid
In the intricate world of organic chemistry, understanding the detailed chemical profile of intermediates is crucial for successful synthesis and product development. 4-Bromo-2-fluorobenzoic acid, identified by CAS number 112704-79-7, is a compound whose properties lend themselves to a wide array of synthetic applications. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing comprehensive information and high-quality supply of such essential chemicals.
The molecular structure of 4-Bromo-2-fluorobenzoic acid is key to its utility. It is a substituted benzoic acid, featuring a bromine atom at the para position and a fluorine atom at the ortho position relative to the carboxyl group. This specific arrangement of electron-withdrawing halogens significantly influences the acidity of the carboxyl group and the reactivity of the aromatic ring. The compound’s molecular formula is C7H4BrFO2, with a molecular weight of approximately 219.01 g/mol. Its physical form is typically a solid, with a melting point reported between 211-215 °C. This solid state at room temperature simplifies handling and storage.
Chemically, 4-Bromo-2-fluorobenzoic acid is highly valuable for its participation in cross-coupling reactions. The carbon-bromine bond is particularly susceptible to oxidative addition by palladium catalysts, initiating catalytic cycles that form new carbon-carbon or carbon-heteroatom bonds. This makes it an ideal starting material for creating more complex organic molecules. Researchers often investigate various 4-Bromo-2-fluorobenzoic acid applications to leverage these properties in their synthetic strategies.
The compound's uses are predominantly as an intermediate. In the pharmaceutical industry, it serves as a critical building block for synthesizing active pharmaceutical ingredients (APIs). It can be incorporated into drug molecules to enhance efficacy, alter metabolic pathways, or improve pharmacokinetic properties. The ability to efficiently buy 4-Bromo-2-fluorobenzoic acid from reliable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. is vital for pharmaceutical research and development pipelines.
Furthermore, the fluorine substituent adds another dimension to its chemical profile. Fluorine is known to increase lipophilicity and metabolic stability in drug molecules. Its presence can also subtly alter the electronic properties of the aromatic ring, influencing the regioselectivity of subsequent reactions. For manufacturers and researchers, understanding the 4-Bromo-2-fluorobenzoic acid price is an important consideration when planning large-scale syntheses.
In conclusion, 4-Bromo-2-fluorobenzoic acid is a powerful and versatile chemical intermediate whose properties are well-suited for advanced organic synthesis. Its well-defined chemical profile, combined with its utility in pharmaceutical and fine chemical production, makes it an indispensable component in the modern chemist's toolkit. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing this essential compound with the highest standards of quality and service.
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“In the intricate world of organic chemistry, understanding the detailed chemical profile of intermediates is crucial for successful synthesis and product development.”
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“4-Bromo-2-fluorobenzoic acid, identified by CAS number 112704-79-7, is a compound whose properties lend themselves to a wide array of synthetic applications.”