At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing high-quality chemical intermediates that serve as the backbone for scientific advancement and industrial innovation. Among our key offerings is 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride, commonly referred to as EDC HCl. This compound is a highly versatile carbodiimide coupling agent, renowned for its efficacy in a wide array of organic synthesis applications, particularly in the realm of peptide and protein chemistry.

The chemical structure of EDC HCl is designed for optimal reactivity and ease of handling. As a hydrochloride salt, it presents as a white to off-white solid, which is a stable form suitable for storage and transport. Its melting point typically falls within the range of 106-116 °C, indicating its solid state under standard laboratory conditions. The purity of EDC HCl is a critical factor for its applications, and NINGBO INNO PHARMCHEM CO.,LTD. ensures high levels of purity, typically ≥98.0%, to guarantee reliable and reproducible results in synthesis.

The primary mechanism by which EDC HCl operates is by activating carboxyl groups. This activation transforms the carboxyl group into a reactive intermediate that readily forms amide bonds with amines, or ester bonds with alcohols. This fundamental reaction is the basis for its extensive use in peptide synthesis, where it links amino acids together to form peptides. In bioconjugation, this same reactivity allows for the covalent attachment of diverse molecules, such as drugs, labels, or polymers, to proteins or other biomolecules. The water-soluble nature of the by-product, N-(3-dimethylaminopropyl)-N'-ethylurea (EDU), is a significant practical advantage, allowing for easy separation from the desired product through simple aqueous extraction or chromatography.

Beyond these core applications, EDC HCl finds utility in polymer modification, diagnostics, and even in the development of certain pharmaceutical formulations. Its ability to function efficiently under mild conditions, often at room temperature and neutral pH, preserves the integrity of sensitive substrates. NINGBO INNO PHARMCHEM CO.,LTD. prioritizes the quality and consistency of our EDC HCl, ensuring that researchers and manufacturers have access to a dependable reagent for their critical chemical synthesis needs. Investing in high-quality EDC HCl from NINGBO INNO PHARMCHEM CO.,LTD. is an investment in the success of your research and development endeavors.