4-Bromo-2-chloropyridine, identified by its CAS number 73583-37-6, is a fundamental building block in organic synthesis, known for its reactivity and versatility. Understanding its physical and chemical properties is paramount for its effective and safe utilization in laboratory and industrial settings. NINGBO INNO PHARMCHEM CO.,LTD. provides this essential chemical and emphasizes the importance of proper handling and storage to maintain its integrity and ensure user safety.

The physical characteristics of 4-Bromo-2-chloropyridine include a density of 1.7336 and a melting point of 27°C. This indicates that at room temperature, it is likely to exist as a solid or a low-melting solid. Its boiling point is recorded at 70°C, and a flash point of 225°F. The refractive index is 1.5900, providing a key parameter for identification and quality control. Typically appearing as a gray-white crystal, its appearance can vary slightly depending on purity and processing, often presenting as colorless to pale yellow. These precise specifications are crucial for applications where exact chemical composition is critical.

Chemically, 4-Bromo-2-chloropyridine is characterized by the presence of two different halogen atoms on the pyridine ring. This structural feature imparts distinct reactivity. The chlorine atom at the 2-position and the bromine atom at the 4-position can both participate in nucleophilic substitution reactions, although their reactivity may differ. Furthermore, these halogens are excellent leaving groups, making the compound amenable to various cross-coupling reactions, such as Suzuki, Sonogashira, and Stille couplings. These reactions are fundamental in constructing carbon-carbon bonds, a critical step in synthesizing complex organic molecules. Therefore, the ability to buy 4-Bromo-2-chloropyridine with guaranteed purity from suppliers like NINGBO INNO PHARMCHEM CO.,LTD. is vital for researchers.

Proper handling and storage of 4-Bromo-2-chloropyridine are essential to maintain its quality and ensure safety. It is recommended to store the compound in a cool, well-ventilated place, away from incompatible materials and ignition sources. Due to its chemical nature, direct contact with skin, eyes, and clothing should be avoided. Appropriate personal protective equipment (PPE), including gloves, safety glasses, and lab coats, should always be worn when handling this substance. Inhalation of dust or vapors should also be prevented by working in a well-ventilated area or fume hood. Understanding the safety data sheet (SDS) for CAS 73583-37-6 is crucial for anyone working with this intermediate.

NINGBO INNO PHARMCHEM CO.,LTD. prioritizes the quality and safety of its products. We ensure that our 4-Bromo-2-chloropyridine is packaged in appropriate containers, typically 25 kg drums, and can accommodate custom packaging requirements. By adhering to strict quality control measures and providing comprehensive product information, we aim to facilitate the successful and safe application of this important organic synthesis intermediate in your research and development endeavors.