For chemists and researchers working with organic intermediates, a thorough understanding of a compound's properties and safe handling procedures is crucial. 4-Bromo-2-iodophenol, a valuable compound available from NINGBO INNO PHARMCHEM CO.,LTD., requires specific knowledge regarding its chemical characteristics. This article outlines the key properties and essential handling guidelines for this important intermediate.

4-Bromo-2-iodophenol, identified by CAS 207115-22-8, is a di-halogenated phenol with a molecular formula of C6H4BrIO and a molecular weight of approximately 298.91 g/mol. Its physical appearance is typically described as a white to light yellow or light orange powder or crystalline solid. The compound exhibits a melting point around 90℃, making it a solid at standard room temperatures. Its boiling point is approximately 243.0±25.0℃ at 760 Torr, and its density is around 2.369±0.06 g/cm3 at 20℃.

The chemical reactivity of 4-Bromo-2-iodophenol is largely dictated by the presence of the hydroxyl group and the two halogen atoms (bromine and iodine) on the aromatic ring. These substituents offer multiple sites for synthetic modification. The iodine atom, being a good leaving group, is particularly amenable to various transition metal-catalyzed cross-coupling reactions, such as Suzuki, Stille, and Sonogashira couplings. The bromine atom can also participate in similar reactions, or it can be transformed through other chemical processes. Understanding these CAS 207115-22-8 chemical properties is vital for successful 4-bromo-2-iodophenol applications in synthesis.

Regarding storage and handling, it is recommended that 4-Bromo-2-iodophenol be kept in a dark place under an inert atmosphere, such as nitrogen or argon, and stored at refrigerated temperatures, typically between 2-8℃. This storage condition helps to maintain its stability and prevent degradation, which can occur due to exposure to light, air, or moisture. Proper ventilation should be ensured when handling the compound, and appropriate personal protective equipment (PPE), including gloves, eye protection, and lab coats, should always be worn.

While the synthesis of 4-Bromo-2-iodophenol involves controlled chemical reactions, users should be aware of potential hazards and consult the Material Safety Data Sheet (MSDS) for comprehensive safety information. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality products along with necessary information to ensure safe and effective use.

In summary, 4-Bromo-2-iodophenol is a synthetically valuable intermediate with well-defined chemical properties. By adhering to recommended storage and handling procedures, researchers can maximize its utility in various chemical endeavors. NINGBO INNO PHARMCHEM CO.,LTD. supports the scientific community by providing this essential compound and the information needed for its responsible application.