A foundational understanding of chemical properties and synthesis pathways is essential for chemists working with versatile intermediates. 1-Chloro-3-iodopropane (CAS: 6940-76-7) is one such compound, valued for its dual halogen functionality and its role in a multitude of organic transformations. Ningbo Inno Pharmchem Co., Ltd. offers insights into the chemical nature of this important intermediate.

1-Chloro-3-iodopropane is classified as a haloalkane, featuring a three-carbon propane backbone substituted with a chlorine atom at the first carbon and an iodine atom at the third carbon. Its molecular formula is C3H6ClI, with a molecular weight of approximately 204.44 g/mol. Physically, it is described as a colorless to pale yellow liquid. The compound exhibits a boiling point in the range of 170-172°C and a density of about 1.904 g/cm³. Its refractive index is typically around 1.548, indicating its specific optical properties.

The synthesis of 1-Chloro-3-iodopropane typically involves reactions that introduce chlorine and iodine atoms onto a propane skeleton. While specific proprietary methods may vary, common approaches involve halogen exchange reactions or direct halogenation processes. The challenge in synthesis lies in achieving high purity and selectivity, ensuring that the desired product is formed with minimal byproducts. The ability to purchase 1-Chloro-3-iodopropane with high purity (>98%) from suppliers like Ningbo Inno Pharmchem Co., Ltd. simplifies the process for end-users.

The chemical reactivity of 1-Chloro-3-iodopropane stems from the presence of two different halogens. The carbon-iodine bond is generally weaker and more polarizable than the carbon-chlorine bond, making the iodine atom a better leaving group in nucleophilic substitution reactions. This differential reactivity is key to its utility in sequential functionalization. For instance, a nucleophile can selectively displace the iodide, leaving the chloride intact for a subsequent reaction or vice-versa, depending on the reaction conditions and reagents used.

These reactions are fundamental to its role in organic synthesis. 1-Chloro-3-iodopropane is frequently used as an alkylating agent, introducing the 3-chloropropyl group onto various nucleophiles. It is also a precursor for creating other dihaloalkanes or cyclic compounds. The price of 1-Chloro-3-iodopropane can fluctuate based on market demand and production costs, but its value as a versatile intermediate often outweighs these considerations.

For researchers and industrial chemists, understanding the detailed chemical properties and potential 1-Chloro-3-iodopropane applications is crucial for successful experimental design and process optimization. Ningbo Inno Pharmchem Co., Ltd. is dedicated to providing high-quality chemical intermediates and technical support to ensure clients can effectively utilize compounds like 1-Chloro-3-iodopropane.

In conclusion, 1-Chloro-3-iodopropane is a vital chemical intermediate whose properties make it invaluable in organic synthesis. Its controlled synthesis and high purity, as offered by Ningbo Inno Pharmchem Co., Ltd., enable its widespread use in developing pharmaceuticals, agrochemicals, and other fine chemicals.