A thorough understanding of a chemical compound's properties and synthesis is fundamental to its effective and safe utilization. 4-Iodoanisole, known by its CAS number 696-62-8, is an aromatic ether whose chemical characteristics make it highly valuable in various industrial processes. Its molecular formula, C7H7IO, hints at its structure, which includes a benzene ring substituted with both an iodine atom and a methoxy group. This unique combination dictates its reactivity, solubility, and physical state, providing chemists with a predictable and useful reagent.

Key chemical properties of 4-Iodoanisole include its solubility profile: it is readily soluble in common organic solvents like ethanol, ether, and chloroform, but exhibits insolubility in water. This characteristic is important for purification processes and reaction solvent selection. Physically, it typically appears as a colorless to pale yellow liquid or crystalline solid, with a melting point often cited in the range of 50-53°C and a boiling point around 237-239°C. The presence of the iodine atom makes it light-sensitive, necessitating storage in amber bottles away from light to maintain its integrity. The synthesis of 4-iodoanisole commonly involves the iodination of anisole using iodine chloride in glacial acetic acid, followed by purification steps like recrystallization or distillation under reduced pressure. Ensuring high purity, often above 98% via GC, is critical for its downstream applications, a standard upheld by suppliers like NINGBO INNO PHARMCHEM CO.,LTD.

The reliable synthesis and detailed characterization of 4-iodoanisole are essential for its widespread use in pharmaceutical intermediates, agrochemicals, and other fine chemical applications. By understanding these fundamental aspects, researchers and manufacturers can effectively integrate this compound into their synthetic strategies, achieving desired outcomes with greater precision and efficiency. The ongoing efforts in optimizing its synthesis and characterizing its properties by companies such as NINGBO INNO PHARMCHEM CO.,LTD. ensure its continued availability and utility for the scientific community.