NINGBO INNO PHARMCHEM CO.,LTD. is a premier supplier of chemical intermediates, and we are pleased to offer a detailed look at Diazoacetylbenzene (CAS 3282-32-4), also known as 2-diazo-1-phenylethanone. This compound is a vital component in various chemical processes, owing to its distinct chemical properties and established synthesis routes.

Diazoacetylbenzene is a pale yellow solid with a melting point of approximately 49°C. Its molecular formula is C8H6N2O, and it has a molecular weight of 146.15. The defining feature of this molecule is the diazo group (-N2=C), which is attached to a carbonyl group and a phenyl ring. This diazo functionality makes it a highly reactive and versatile intermediate in organic synthesis. The presence of the diazo group enables it to undergo a range of transformations, including the generation of carbenes and carbenoids upon decomposition. These reactive species are pivotal in forming new carbon-carbon bonds, making Diazoacetylbenzene invaluable for constructing complex organic molecules.

The synthesis of Diazoacetylbenzene is typically accomplished through the reaction of an aroyl chloride, such as benzoyl chloride, with diazomethane. This reaction, often carried out in the presence of a base like triethylamine to neutralize the liberated hydrogen chloride, is a general method for preparing diazoketones. Alternatively, improved methods involve the acylation of lithium enolates with specific trifluoroacetate derivatives followed by reaction with mesyl azide. The careful execution of these synthetic procedures is crucial to ensure high purity and yield. For those seeking to buy Diazoacetylbenzene, understanding these synthetic pathways provides confidence in the product's quality and reliability.

Beyond its role in carbene chemistry, Diazoacetylbenzene is also utilized in other significant applications. It serves as a 1,3-dipole in cycloaddition reactions, facilitating the synthesis of various heterocyclic compounds, which are essential structural motifs in many pharmaceuticals and agrochemicals. Furthermore, it is used in the preparation of diazo dyes for the textile industry, contributing to vibrant and durable coloration. The compound's broad applicability underscores its importance as a versatile organic intermediate.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality chemical intermediates to researchers and industries worldwide. Our Diazoacetylbenzene (CAS 3282-32-4) is produced under strict quality control measures to meet the demands of advanced chemical synthesis. We understand that the Diazoacetylbenzene price must be competitive, and we strive to offer excellent value for a product that supports critical research and industrial processes. By choosing NINGBO INNO PHARMCHEM CO.,LTD., you ensure access to reliable and well-characterized chemical compounds.

In conclusion, Diazoacetylbenzene is a key organic intermediate with a rich chemical profile. Its reactivity, derived from the diazo group, makes it essential for carbene chemistry, heterocycle synthesis, and dye production. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a trusted source for this indispensable compound, supporting innovation across the chemical landscape.