For chemists and researchers working with organic compounds, a thorough understanding of reagent properties and safe handling practices is paramount. 2-Iodopropane, also known as isopropyl iodide (CAS No. 75-30-9), is a valuable reagent with specific characteristics that dictate its use and require careful management. This guide aims to provide essential information on its properties, applications, and safety considerations, ensuring its effective and responsible utilization in laboratory and industrial settings.

Physically, 2-iodopropane is typically described as a clear, colorless to pale yellow liquid. It possesses a characteristic strong iodine odor, which can serve as an initial indicator of its presence. Its molecular formula is C3H7I, with a molecular weight of approximately 169.99 g/mol. Key physical properties include a boiling point around 87-90°C and a density of roughly 1.703 g/mL at 25°C. These properties are important for determining appropriate reaction conditions and purification methods. For instance, its relatively low boiling point means it can be readily removed via distillation, a common technique in organic synthesis.

Chemically, 2-iodopropane is a versatile alkylating and halogenating agent. Its primary utility stems from its ability to readily undergo nucleophilic substitution reactions, where the iodine atom acts as a good leaving group. This characteristic makes it an excellent choice for introducing the isopropyl group into various organic molecules, a process fundamental to the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. The compound's reactivity is generally considered good, though the presence of a stabilizing agent like copper, as found in some commercial preparations, can modulate this reactivity and improve overall stability, particularly against decomposition.

When handling 2-iodopropane, safety is a primary concern. As with many halogenated organic compounds, it is important to avoid contact with skin, eyes, and clothing. Appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles, and a lab coat, should always be worn. Work should be conducted in a well-ventilated area, preferably a fume hood, to prevent inhalation of vapors. Its flammability should also be noted; it has a flash point of around 42.2 °C, meaning it can ignite if exposed to an ignition source at or above this temperature. Therefore, it should be kept away from open flames and heat sources.

Storage recommendations for 2-iodopropane typically involve keeping it in a tightly sealed container in a cool, dry, and well-ventilated place, often at room temperature, away from direct sunlight and incompatible materials. Stabilized forms, often containing copper, are generally more resistant to decomposition. NINGBO INNO PHARMCHEM CO.,LTD. ensures its 2-iodopropane products meet stringent quality and safety standards, providing reliable reagents for research and industrial use. Understanding these properties and handling procedures is key to unlocking the full potential of 2-iodopropane in chemical endeavors.