Unveiling the Chemical Properties of AEEA-AEEA (CAS 1143516-05-5): A Versatile Organic Intermediate
In the intricate world of organic synthesis, understanding the fundamental properties of chemical intermediates is key to successful innovation. AEEA-AEEA, identified by its CAS number 1143516-05-5, stands out as a versatile organic intermediate whose unique chemical profile facilitates its use in a range of advanced applications. NINGBO INNO PHARMCHEM CO.,LTD. emphasizes the importance of these intrinsic properties in unlocking the full potential of this compound.
AEEA-AEEA, or 17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic acid, is characterized by its molecular formula C₁₂H₂₄N₂O₇ and a molecular weight of approximately 308.33 g/mol. This structure is essentially a dimeric form, where two aminoethylethanolamine (AEEA) units are linked. This arrangement provides a unique combination of functional groups: a terminal primary amine, an internal amide linkage, and a terminal carboxylic acid, all bridged by flexible ether linkages derived from polyethylene glycol (PEG) chains. This architectural complexity is the source of its versatility.
The terminal primary amine group (-NH₂) is a highly reactive nucleophilic site, readily participating in reactions such as acylation, alkylation, and conjugation. This makes AEEA-AEEA an excellent building block for creating more complex molecules. The internal amide bond (-CONH-) offers a stable linkage under physiological conditions but can be designed to be cleavable under specific chemical or enzymatic triggers, a feature highly sought after in drug delivery systems and bioconjugation.
The carboxylic acid group (-COOH) at the other end of the molecule provides another key point for conjugation, typically through esterification or amide bond formation with other molecules. The presence of multiple ether linkages within the molecule contributes to its solubility in aqueous and polar organic solvents, and also imparts flexibility to structures into which it is incorporated. This flexibility is crucial in applications like Antibody-Drug Conjugates (ADCs) and PROTACs, where the linker must position other molecular components optimally.
The AEEA-AEEA applications are directly influenced by these chemical properties. For instance, its ability to react with both amines and carboxylic acids allows it to function as a versatile linker in synthesizing complex biomolecules. Researchers leverage these characteristics for precise peptide modifications and the construction of targeted therapeutic agents. The consistent quality and purity of AEEA-AEEA, as supplied by manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., are paramount to ensuring predictable reactivity and successful outcomes in demanding synthesis projects.
Understanding the nuances of CAS 1143516-05-5 chemical properties is essential for chemists and researchers aiming to utilize this intermediate effectively. Its predictable reactivity, coupled with its structural features, positions AEEA-AEEA as a valuable asset in the development of advanced pharmaceuticals, diagnostics, and research tools. The ongoing exploration of its chemical behavior continues to uncover new avenues for its application in cutting-edge scientific endeavors.
In conclusion, the chemical properties of AEEA-AEEA are a testament to its utility as a versatile organic intermediate. Its unique combination of functional groups and structural flexibility makes it an indispensable component in various advanced synthesis protocols, from peptide functionalization to the creation of sophisticated drug delivery systems. The continued study and application of these properties by NINGBO INNO PHARMCHEM CO.,LTD. and the broader scientific community will undoubtedly lead to further breakthroughs.
Perspectives & Insights
Nano Explorer 01
“Understanding the nuances of CAS 1143516-05-5 chemical properties is essential for chemists and researchers aiming to utilize this intermediate effectively.”
Data Catalyst One
“Its predictable reactivity, coupled with its structural features, positions AEEA-AEEA as a valuable asset in the development of advanced pharmaceuticals, diagnostics, and research tools.”
Chem Thinker Labs
“The ongoing exploration of its chemical behavior continues to uncover new avenues for its application in cutting-edge scientific endeavors.”