In the intricate world of organic synthesis, the selection of appropriate intermediates is crucial for achieving desired molecular targets efficiently and effectively. 3-Chloro-5-isoquinolinamine, bearing the CAS number 58142-49-7, exemplifies such an intermediate, offering a unique structural foundation for a multitude of advanced chemical transformations.

The molecule's identity as a substituted isoquinoline provides a robust aromatic framework that is inherently stable yet amenable to diverse chemical manipulations. The specific functionalization of this isoquinoline core, namely the presence of a chlorine atom at the 3-position and an amine group at the 5-position, dictates its reactivity and broadens its applicability. These features position it as a highly valuable fine chemical intermediate in various synthetic pathways.

For chemists working in pharmaceutical research, this compound is particularly significant. It serves as a key building block in the synthesis of numerous Active Pharmaceutical Ingredients (APIs). The amine group can readily undergo reactions like acylation or alkylation, allowing for the attachment of complex side chains that are often essential for a drug's biological activity. Simultaneously, the chlorine atom can act as a leaving group in nucleophilic substitution reactions or participate in metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling the formation of new carbon-carbon or carbon-nitrogen bonds. This versatility makes it an ideal starting point for constructing intricate molecular architectures common in modern drug design, thus acting as a critical API intermediate.

The consistent quality of 3-Chloro-5-isoquinolinamine, with a typical purity of 98%, is a critical factor for reliable and reproducible synthetic outcomes. This purity minimizes side reactions and simplifies purification processes, which are often time-consuming and costly in multistep syntheses. As a white or light yellow crystalline powder, it is easily handled and measured, further streamlining laboratory operations and production workflows.

Moreover, the compound’s availability from reputable suppliers ensures that researchers and manufacturers have consistent access to this essential reagent. This reliability is vital for maintaining project timelines and facilitating the scale-up of synthetic processes from laboratory bench to industrial production. The global logistical network supporting the distribution of such fine chemicals ensures that these critical building blocks reach chemists worldwide, fostering advancements in organic chemistry and related fields.

In essence, 3-Chloro-5-isoquinolinamine (CAS 58142-49-7) is more than just a chemical compound; it is a cornerstone for innovation in advanced organic chemistry. Its unique structural attributes and reactive functional groups make it an indispensable intermediate for creating complex molecules, driving progress in pharmaceutical development and the broader fine chemical industry.