4-Amino-3,5-dichloropyridine: A Fundamental Building Block for Roflumilast and Beyond
The pharmaceutical industry relies heavily on a robust supply chain of high-quality chemical intermediates to develop and manufacture life-saving medications. Among these crucial compounds is 4-Amino-3,5-dichloropyridine (CAS No. 22889-78-7), an essential building block primarily used in the synthesis of Roflumilast. Roflumilast is a groundbreaking treatment for chronic obstructive pulmonary disease (COPD), a debilitating respiratory condition. NINGBO INNO PHARMCHEM CO.,LTD., a leading 4-Amino-3,5-dichloropyridine manufacturer in China, is proud to contribute to this vital sector by providing a reliable source of this critical intermediate.
Understanding the chemical characteristics of 4-Amino-3,5-dichloropyridine is fundamental for its effective application. The compound's molecular formula is C5H4Cl2N2, with a molecular weight of 163.00500. It is typically supplied as a white needle crystal, exhibiting properties such as a density of 1.497 g/cm³, a melting point of 158-162°C, and a boiling point of 250.8°C. These specifications ensure its stability and predictability in chemical reactions. For those seeking to buy 4-Amino-3,5-dichloropyridine, it is imperative to choose a 4-Amino-3,5-dichloropyridine supplier in China that guarantees high purity, often assayed at u226598.0% via HPLC. This commitment to quality is a hallmark of our manufacturing process.
The primary and most significant application of 4-Amino-3,5-dichloropyridine is its role as a key intermediate in the synthesis of Roflumilast. Roflumilast, a selective phosphodiesterase-4 (PDE4) inhibitor, is vital in managing the inflammatory processes associated with COPD. The structural features of 4-Amino-3,5-dichloropyridine make it an ideal precursor for the chemical transformations required to produce Roflumilast. The accuracy and efficiency of this synthesis are directly influenced by the quality of the starting materials. Therefore, partnering with a reputable 4-Amino-3,5-dichloropyridine manufacturer in China like NINGBO INNO PHARMCHEM CO.,LTD. is crucial for ensuring the integrity of the final drug product.
Beyond its primary pharmaceutical application, 4-Amino-3,5-dichloropyridine holds promise in broader fine chemical manufacturing. Its unique chlorinated pyridine structure serves as a versatile scaffold for synthesizing a range of complex organic molecules. As research and development in the chemical sciences continue to advance, the demand for specialized intermediates such as this compound is expected to grow. A dependable 4-Amino-3,5-dichloropyridine supplier in China is essential for researchers and manufacturers looking to explore new chemical frontiers and develop innovative products. Our capabilities extend to supporting various custom synthesis projects.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality chemical solutions. We offer competitive pricing for 4-Amino-3,5-dichloropyridine and are equipped to handle orders ranging from laboratory scale to commercial production. If you have any inquiries about the purchase of 4-Amino-3,5-dichloropyridine or wish to obtain a quotation, our professional sales team is ready to assist you. Let us be your trusted partner in sourcing essential chemical building blocks from China.
Perspectives & Insights
Molecule Vision 7
“, a leading 4-Amino-3,5-dichloropyridine manufacturer in China, is proud to contribute to this vital sector by providing a reliable source of this critical intermediate.”
Alpha Origin 24
“Understanding the chemical characteristics of 4-Amino-3,5-dichloropyridine is fundamental for its effective application.”
Future Analyst X
“It is typically supplied as a white needle crystal, exhibiting properties such as a density of 1.”