At NINGBO INNO PHARMCHEM CO.,LTD., we recognize that the foundation of groundbreaking chemical innovation often lies in versatile and reliable building blocks. 4-Ethynylaniline, identified by CAS number 14235-81-5, stands out as one such fundamental component in organic synthesis. Possessing both a reactive terminal alkyne and an amine group on an aromatic ring, this compound offers a rich platform for constructing a wide array of complex organic molecules used across multiple industries.

The primary strength of 4-ethynylaniline in general organic synthesis stems from its dual reactivity. The terminal alkyne moiety is a versatile functional group that can undergo numerous transformations. It is highly amenable to various metal-catalyzed coupling reactions, such as Sonogashira coupling, which allows for the formation of new carbon-carbon bonds by linking alkynes with aryl or vinyl halides. This capability is critical for building extended conjugated systems found in advanced materials or complex pharmaceutical structures.

Simultaneously, the aniline portion of the molecule provides a nucleophilic amine group. This amine can be readily functionalized through acylation, alkylation, or used in condensation reactions to form imines or amides. These reactions are standard procedures in organic synthesis for creating diverse derivative structures or for linking the molecule to other scaffolds. For instance, the amine group can be protected, allowing selective reactions at the alkyne, and then deprotected for further transformations.

The synergy between these two functional groups makes 4-ethynylaniline an invaluable starting material for synthetic chemists. Its application spans the creation of dyes, agrochemicals, electronic materials, and, as previously highlighted, pharmaceuticals. The ability to strategically manipulate either the alkyne or the amine group, or both in sequence, provides immense synthetic flexibility.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying chemists with the high-quality 4-ethynylaniline necessary for these intricate synthetic pathways. We ensure that our product meets stringent purity standards, which is crucial for achieving predictable and high-yielding reactions in complex multi-step syntheses. By providing a reliable source for this foundational building block, we aim to accelerate your research and production efforts.

Whether your project involves intricate natural product synthesis, the development of novel catalysts, or the creation of specialized functional materials, 4-ethynylaniline from NINGBO INNO PHARMCHEM CO.,LTD. offers the versatility and quality you need. Partner with us to build your next synthetic success.