5-Bromo-2-chloropyrimidine: A Versatile Building Block in Pharmaceutical and Chemical Synthesis
While 5-Bromo-2-chloropyrimidine (CAS: 32779-36-5) is famously recognized as a critical intermediate in the synthesis of Macitentan, its utility extends far beyond this specific application. As a heterocycle featuring both bromine and chlorine substituents on a pyrimidine ring, this compound possesses a versatile reactivity profile that makes it a valuable asset in broader pharmaceutical and chemical synthesis endeavors. NINGBO INNO PHARMCHEM CO.,LTD. offers this essential compound to researchers and manufacturers worldwide.
The presence of two distinct halogen atoms on the pyrimidine core allows for selective functionalization through various chemical reactions. One of the most significant applications, besides its role in the synthesis of macitentan active pharmaceutical ingredient, is its participation in cross-coupling reactions. These reactions, such as Suzuki, Stille, or Buchwald-Hartwig couplings, are indispensable tools for constructing complex organic molecules. The ability to efficiently form carbon-carbon or carbon-heteroatom bonds using intermediates like 5-Bromo-2-chloropyrimidine is what drives innovation in drug discovery.
As a key component within the realm of chemical building blocks online, 5-Bromo-2-chloropyrimidine serves as a starting point for creating a diverse array of compounds. Researchers often seek out such versatile intermediates for developing novel drug candidates targeting various diseases. The molecular formula C4H2BrClN2 and its stable crystalline powder form contribute to its ease of handling and reaction. Companies looking for a reliable macitentan intermediate supplier often find that suppliers like NINGBO INNO PHARMCHEM CO.,LTD. also cater to broader research needs.
The demand for high-quality 5-bromo-2-chloropyrimidine CAS 32779-36-5 underscores its importance in the fine chemicals sector. Its application in creating active pharmaceutical ingredients (APIs) for a range of therapeutic areas, not just cardiovascular diseases, makes it a versatile intermediate. Whether it's for targeted drug delivery systems or exploring new chemical scaffolds, this compound provides a robust platform for synthetic chemists.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing a consistent supply of this vital chemical intermediate, enabling advancements in both established pharmaceutical production and cutting-edge chemical research. By offering reliable access to pharmaceutical intermediates like 5-Bromo-2-chloropyrimidine, the company empowers the scientific community to push the boundaries of what is possible in chemical synthesis and drug development.
Perspectives & Insights
Data Seeker X
“Whether it's for targeted drug delivery systems or exploring new chemical scaffolds, this compound provides a robust platform for synthetic chemists.”
Chem Reader AI
“is committed to providing a consistent supply of this vital chemical intermediate, enabling advancements in both established pharmaceutical production and cutting-edge chemical research.”
Agile Vision 2025
“By offering reliable access to pharmaceutical intermediates like 5-Bromo-2-chloropyrimidine, the company empowers the scientific community to push the boundaries of what is possible in chemical synthesis and drug development.”