NINGBO INNO PHARMCHEM CO.,LTD. is a trusted partner for researchers in biochemistry and molecular biology, providing essential reagents for cutting-edge studies. N-Methyl-L-Alanine (CAS 600-21-5) is a key compound utilized in advanced biochemical assays, particularly for elucidating the complex mechanisms of amino acid transport.

Amino acid transporters are vital proteins embedded in cell membranes that regulate the uptake and efflux of amino acids, crucial for cellular function, nutrient sensing, and signaling. Studying these transporters is essential for understanding various physiological processes and diseases. N-Methyl-L-Alanine serves as an excellent tool in these investigations due to its structural similarity to natural amino acids and its distinct properties, such as its stability and the presence of an N-methyl group.

Researchers commonly use N-Methyl-L-Alanine in assays designed to characterize specific amino acid transport systems, such as the System A transporter. It can act as a competitive inhibitor or a substrate analog, allowing scientists to study the kinetics of transport, identify specific binding sites, and determine the affinity of transporters for different molecules. For instance, in studies involving perfused rat pancreatic ducts, radiolabeled N-Methyl-L-Alanine can be used to track its uptake and observe its competitive interaction with other substrates, providing quantitative data on transport rates. NINGBO INNO PHARMCHEM CO.,LTD. supplies high-purity N-Methyl-L-Alanine, ensuring the accuracy and reliability of such experimental results.

Furthermore, the compound is instrumental in the synthesis of specialized peptides and protein analogues. By incorporating N-methylated amino acids, researchers can create modified peptides with altered conformational properties, increased stability, and improved membrane permeability. These modified peptides are invaluable for drug discovery, protein engineering, and understanding structure-activity relationships. The ability to precisely engineer peptide sequences using building blocks like N-Methyl-L-Alanine, provided by NINGBO INNO PHARMCHEM CO.,LTD., opens new possibilities in biomolecular research.

In summary, N-Methyl-L-Alanine is a critical reagent for advanced biochemical assays, aiding in the detailed study of amino acid transport mechanisms and the synthesis of novel biomolecules. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting the scientific community by providing this essential compound for groundbreaking research.