NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing high-quality pharmaceutical intermediates that are essential for groundbreaking research and drug development. AM2394 (CAS: 1442684-77-6) is a prime example of such a compound, recognized for its potent glucokinase activator (GKA) properties and its significant role in the study of metabolic syndrome and type 2 diabetes.

Metabolic syndrome is a complex cluster of conditions that increase the risk of heart disease, stroke, and diabetes. At the heart of many metabolic dysfunctions is impaired glucose regulation, often linked to the activity of glucokinase. AM2394 acts as a potent activator of glucokinase, with a well-established EC50 of 60 nM. This means it effectively enhances the enzyme's ability to phosphorylate glucose, a crucial step in cellular energy utilization and insulin secretion. By restoring or enhancing glucokinase function, AM2394 offers a valuable avenue for therapeutic exploration in metabolic syndrome.

The journey from laboratory research to potential therapeutic application requires compounds with favorable pharmacokinetic properties. AM2394 possesses good oral bioavailability, allowing it to be administered effectively in preclinical studies. Its demonstrated ability to lower plasma glucose levels in animal models of diabetes, as observed during oral glucose tolerance tests, highlights its therapeutic potential. This makes AM2394 an indispensable pharmaceutical intermediate for companies developing novel treatments for metabolic disorders. Sourcing AM2394 from a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures the purity and consistency needed for such critical research.

For researchers in drug discovery, AM2394 serves not only as a research chemical but also as a foundational component for developing new therapeutic agents. Its well-defined mechanism of action and established efficacy in relevant models make it an attractive starting point for medicinal chemistry efforts. The availability of AM2394 at a competitive price, coupled with its high quality, further supports its widespread use in academic and industrial research settings focused on metabolic syndrome and diabetes. Buying AM2394 from NINGBO INNO PHARMCHEM CO.,LTD. means investing in reliable research materials.

In conclusion, AM2394 is a pivotal pharmaceutical intermediate and a potent glucokinase activator that significantly contributes to metabolic syndrome research. Its ability to enhance glucose regulation and its promising therapeutic profile make it a cornerstone for scientists working on diabetes and related metabolic conditions. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying high-quality AM2394, supporting the critical work that leads to advancements in human health.