NINGBO INNO PHARMCHEM CO.,LTD. is a trusted supplier of advanced biochemicals, including AM2394 (CAS: 1442684-77-6), a compound making significant strides in diabetic research. As a potent glucokinase activator, AM2394 is instrumental in understanding and potentially treating diabetes by targeting key mechanisms of glucose homeostasis.

Glucokinase (GK) is a critical enzyme in the liver and pancreatic beta cells, playing a central role in glucose sensing and insulin secretion. Dysregulation of GK activity is strongly implicated in the pathogenesis of type 2 diabetes. AM2394 functions by activating glucokinase, increasing its affinity for glucose with an impressive EC50 of 60 nM. This potent activation enhances glucose phosphorylation, leading to improved glucose disposal and insulin release, thereby contributing to better glycemic control. For researchers focused on diabetic research, the ability to purchase AM2394 of high purity is essential for obtaining reliable results.

The therapeutic potential of AM2394 is further amplified by its favorable pharmacokinetic properties, notably its oral bioavailability. This characteristic allows for effective delivery and action within the body, crucial for developing orally administered diabetes medications. Studies have shown that AM2394 can significantly reduce plasma glucose levels in animal models of diabetes, as evidenced by its performance in oral glucose tolerance tests. Its moderate clearance and good bioavailability across different species make it a versatile tool for a wide range of preclinical investigations. Pharmaceutical suppliers recognize the value of such compounds for their drug development pipelines.

As a company committed to scientific advancement, NINGBO INNO PHARMCHEM CO.,LTD. ensures that AM2394 is produced under strict quality control standards. This guarantees the compound's consistency and purity, making it a reliable choice for sensitive research applications. The availability of AM2394 at a competitive price point makes it an accessible resource for academic institutions and pharmaceutical companies alike, facilitating wider exploration of its therapeutic benefits. Researchers seeking to buy AM2394 can trust our commitment to excellence.

In conclusion, AM2394 is at the forefront of research into novel diabetes treatments, acting as a potent glucokinase activator with excellent bioavailability. Its ability to improve glycemic control in preclinical models positions it as a vital compound for diabetic research. NINGBO INNO PHARMCHEM CO.,LTD. is proud to supply high-quality AM2394, supporting the scientific community in its quest to combat diabetes and improve patient outcomes.