NINGBO INNO PHARMCHEM CO.,LTD. is a leading provider of specialized chemicals for life science research, including AM2394 (CAS: 1442684-77-6). This compound is highly valued for its efficacy as a glucokinase activator (GKA), offering researchers a powerful tool to investigate glucose metabolism and insulin sensitivity.

Glucose metabolism is a fundamental biological process tightly regulated by various enzymes, among which glucokinase plays a pivotal role. Glucokinase is responsible for the initial phosphorylation of glucose in hepatic and pancreatic beta cells, directly influencing glucose sensing and insulin secretion. AM2394, with its potent GKA activity (EC50 = 60 nM), significantly enhances the affinity of glucokinase for glucose. This enhancement leads to improved glucose uptake and metabolism, which is critical for maintaining healthy insulin sensitivity and overall glycemic control. Researchers looking to buy AM2394 for these studies will find it an indispensable research chemical.

The utility of AM2394 is further amplified by its favorable pharmacokinetic profile, including good oral bioavailability. This characteristic makes it suitable for in vivo studies aimed at understanding systemic effects on glucose metabolism and insulin sensitivity. Preclinical studies have demonstrated AM2394's ability to induce a significant reduction in plasma glucose levels during oral glucose tolerance tests in animal models of diabetes. Such findings underscore its potential in developing therapeutic strategies for conditions characterized by insulin resistance and impaired glucose regulation. Pharmaceutical intermediate suppliers play a crucial role in making such compounds available for research.

As a premier supplier, NINGBO INNO PHARMCHEM CO.,LTD. ensures that AM2394 meets the highest standards of purity and quality. This reliability is essential for researchers conducting delicate experiments related to glucose metabolism and insulin signaling. The compound's affordability and availability also contribute to its widespread adoption in both academic and industrial research settings. Whether exploring fundamental metabolic pathways or screening for new drug candidates, AM2394 is a valuable asset.

In essence, AM2394 serves as a critical research chemical for dissecting the complexities of glucose metabolism and insulin sensitivity. Its potent glucokinase activating properties, coupled with its bioavailability, make it an ideal compound for a wide range of biochemical and physiological studies. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality AM2394 to support scientific discovery and advance the understanding and treatment of metabolic diseases.