The online marketplace has revolutionized the procurement of chemical intermediates, offering unprecedented access to a vast array of compounds. For researchers and manufacturers requiring 3-Bromo-2-hydroxypyridine (CAS 13466-43-8), a critical component in pharmaceutical synthesis, navigating this landscape requires careful consideration of several key factors.

Firstly, product quality and purity are paramount. When you intend to buy 3-Bromo-2-hydroxypyridine, always verify the specified purity level, typically indicated by GC or HPLC analysis. A minimum purity of 97% is generally recommended for pharmaceutical intermediate applications to ensure reliable reaction outcomes and prevent contamination of downstream products. Suppliers like NINGBO INNO PHARMCHEM CO.,LTD., a manufacturer in China, usually provide detailed certificates of analysis.

Secondly, supplier reliability is crucial. It is advisable to source from established manufacturers or distributors with a proven track record. Look for companies that have clear contact information, provide comprehensive product details, and offer responsive customer service. Many reputable suppliers will also provide information on their manufacturing capabilities and quality control processes. NINGBO INNO PHARMCHEM CO.,LTD. aims to be such a trusted partner for your chemical building block needs.

Thirdly, pricing and quantity considerations are important. While China is known for competitive pricing, it is essential to compare quotes from multiple suppliers. Consider the unit price in relation to the quantity required, as bulk purchases often offer significant discounts. Understand the minimum order quantity (MOQ) and lead times to ensure alignment with your project schedules. The availability of 3-Bromo-2-hydroxypyridine at favorable price points from Chinese chemical suppliers can significantly impact project budgets.

The applications of 3-Bromo-2-hydroxypyridine, particularly as a precursor in pyrazolopyridine synthesis for $\gamma$-secretase modulators, mean that consistent supply is vital. When buying online, ensure the supplier can meet your ongoing demand, whether for research quantities or larger-scale manufacturing. Familiarize yourself with their shipping policies, payment terms (e.g., T/T, L/C), and any necessary import regulations.

In conclusion, purchasing 3-Bromo-2-hydroxypyridine (CAS 13466-43-8) online requires diligence in selecting a supplier that guarantees quality, reliability, and competitive pricing. By focusing on these aspects, you can secure this essential chemical intermediate effectively, supporting your critical research and manufacturing endeavors.