NINGBO INNO PHARMCHEM CO.,LTD. is a trusted source for high-quality biochemicals that are crucial for advancing scientific understanding. Among our extensive product range, 1-Myristoyl-2-(4-nitrophenylsuccinyl)-sn-glycero-3-phosphocholine (CAS: 273931-53-6), or 14:0 NPS PC for short, stands out as a vital reagent for researchers studying the intricate dynamics of cell membranes.

Cell membranes are complex, fluid structures that play critical roles in cellular transport, signaling, and overall cellular integrity. They are composed of a phospholipid bilayer, with various proteins and other lipid molecules embedded within. Understanding how these components interact and how membrane fluidity and organization affect cellular function is a key area of biological research. 14:0 NPS PC, with its specific lipid structure, offers a unique tool for dissecting these complex phenomena.

The molecule's structure comprises a saturated 14-carbon fatty acid chain (myristoyl) at the sn-1 position, a modified acyl group (4-nitrophenylsuccinyl) at the sn-2 position, and a phosphocholine headgroup. This combination allows researchers to investigate how different fatty acid lengths and substitutions at the sn-2 position can influence membrane properties such as phase transition temperatures, permeability, and protein-lipid interactions. The presence of the nitrophenylsuccinyl group can also introduce specific spectroscopic or chemical handles for advanced studies.

Researchers utilize 14:0 NPS PC in various experimental setups, including liposome formation for studying membrane fusion or drug permeability, and as a component in model membranes to mimic cellular lipid environments. The high purity of our product (≥97%) ensures that experimental results are accurate and reproducible, which is essential for reliable scientific conclusions. By incorporating this specialized lipid, scientists can precisely control the lipid composition of their model systems, leading to a deeper understanding of fundamental membrane processes.

The applications extend to probing enzyme activities that act on phospholipids, such as lipases or phospholipases. The modified structure of 14:0 NPS PC can serve as a substrate to study enzyme specificity and activity, providing valuable data for understanding metabolic pathways and potential drug targets. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying these critical biochemical reagents, thereby supporting the vital work of scientists worldwide in unraveling the complexities of cell membrane dynamics and contributing to advancements in health and biology.