The Chemical Profile of 6-Iodo-1H-indazole: Properties and Handling for Pharmaceutical Use
In the intricate world of pharmaceutical manufacturing, understanding the precise chemical and physical properties of every intermediate is crucial for successful synthesis and product integrity. 6-Iodo-1H-indazole, a vital compound in the production of Axitinib, a targeted cancer therapy, is no exception. Its reliable performance as a building block hinges on its well-defined characteristics, which Ningbo Inno Pharmchem Co., Ltd. meticulously ensures.
The identity of this critical intermediate is clearly established by its CAS number: 261953-36-0. Chemically, it is known as 6-Iodo-1H-indazole, with the molecular formula C7H5IN2 and a molecular weight of 244.03200. These identifiers are fundamental for quality control, regulatory compliance, and precise stoichiometric calculations in synthesis reactions. The compound typically presents itself as a yellow crystalline powder, a physical characteristic that provides an immediate visual cue for its identity and quality.
Beyond its basic identification, the physical and chemical properties of 6-Iodo-1H-indazole offer essential insights for handling and process integration. Its density is reported at 2.082 g/cm³, its boiling point at a high 358.2°C, and its flash point at 170.4°C. The refractive index is 1.788. These parameters are vital for chemical engineers and researchers when designing reaction setups, managing process safety, and ensuring optimal reaction kinetics. The purity standard, typically 98.0% or higher, guarantees that the material is suitable for advanced pharmaceutical applications, minimizing the risk of unwanted side reactions or impurities in the final drug product.
Ningbo Inno Pharmchem Co., Ltd. places a strong emphasis on providing comprehensive information about the 6-iodo-1h-indazole chemical properties to our clients. Whether you are looking to understand the best methods to buy 6-iodo-1h-indazole or need specific data for your research, we offer products that meet rigorous standards. As a key axitinib intermediate, the quality of 6-Iodo-1H-indazole directly impacts the efficacy and safety of the final medication. Therefore, our commitment to delivering high purity 6-iodo-1h-indazole is unwavering.
Proper storage, as recommended in a cool, ventilated place, is also essential to maintain the integrity of 6-Iodo-1H-indazole. By adhering to these guidelines and leveraging the detailed chemical profile, pharmaceutical manufacturers can confidently integrate this intermediate into their production processes, ensuring the consistent and successful synthesis of vital medicines like Axitinib.
Perspectives & Insights
Alpha Spark Labs
“These parameters are vital for chemical engineers and researchers when designing reaction setups, managing process safety, and ensuring optimal reaction kinetics.”
Future Pioneer 88
“0% or higher, guarantees that the material is suitable for advanced pharmaceutical applications, minimizing the risk of unwanted side reactions or impurities in the final drug product.”
Core Explorer Pro
“places a strong emphasis on providing comprehensive information about the 6-iodo-1h-indazole chemical properties to our clients.”