In the realm of sophisticated organic chemistry and pharmaceutical manufacturing, understanding the detailed profiles of key intermediates is paramount. N-(2-Pyrazinylcarbonyl)-L-phenylalanine (CAS: 114457-94-2) is one such compound that plays a crucial role, primarily as an intermediate in the synthesis of Bortezomib, a critical drug in oncology. This article aims to provide a comprehensive overview of its chemical characteristics, applications, and its significance in the broader chemical industry, drawing upon the expertise of manufacturers like NINGBO INNO PHARMCHEM CO.,LTD.

Chemically, N-(2-Pyrazinylcarbonyl)-L-phenylalanine is an organic compound characterized by its specific molecular formula, C14H13N3O3, and a molecular weight of 271.27. Its physical properties typically describe it as a white or off-white powder, indicating a high degree of purity crucial for its intended applications. The specified purity of ≥98% ensures that it meets the rigorous demands of pharmaceutical synthesis, where even minor impurities can affect the final API's efficacy and safety profile. Key physical attributes like density (1.323 g/cm³) and a high flash point (300.8ºC) suggest its stability under various processing conditions, making it a reliable choice for chemical reactions.

The primary and most well-documented application of N-(2-Pyrazinylcarbonyl)-L-phenylalanine is its indispensable role as an intermediate in the synthesis of Bortezomib. Bortezomib is a first-in-class proteasome inhibitor that has significantly improved treatment outcomes for patients with multiple myeloma and mantle cell lymphoma. The development and production of Bortezomib are dependent on the consistent availability of high-quality intermediates, making the N-(2-Pyrazinylcarbonyl)-L-phenylalanine CAS 114457-94-2 a highly sought-after compound in the pharmaceutical supply chain.

Beyond its critical role in Bortezomib synthesis, the compound's structure also suggests potential utility in other areas of medicinal chemistry and organic synthesis. The combination of a pyrazine ring and a modified phenylalanine moiety provides a versatile scaffold for further chemical modifications. As the pharmaceutical industry continues to explore novel therapeutic agents, compounds like this intermediate are invaluable for research and development efforts. NINGBO INNO PHARMCHEM CO.,LTD. actively supports this research by providing access to such specialized chemicals.

The market for pharmaceutical intermediates is highly competitive, with a significant portion of production originating from China. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. are at the forefront, leveraging advanced chemical engineering and stringent quality management systems. Our production capabilities allow for scalable manufacturing, meeting demands from laboratory research quantities to large-scale industrial production. We are committed to providing comprehensive technical support and ensuring that our clients receive not only the chemical product but also the assurance of quality and reliability required for pharmaceutical applications.

In conclusion, N-(2-Pyrazinylcarbonyl)-L-phenylalanine is a vital intermediate whose chemical properties and primary application in Bortezomib synthesis underscore its importance in modern medicine. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a reliable source for this compound, contributing to the advancement of cancer therapies through our dedication to quality and innovation in chemical manufacturing.