The Chemical Profile of Dasabuvir (ABT-333): Properties, Synthesis, and Handling
Dasabuvir (ABT-333), identified by CAS 1132935-63-7, is a vital pharmaceutical intermediate characterized by its molecular formula C26H27N3O5S and a molecular weight of 493.57 g/mol. Commonly known by synonyms such as CS-2000 and Dasabuvir (ABT-333), this compound presents as a white powder with a pale brown to light brown appearance, typically with a melting point exceeding 192°C with decomposition. Its solubility in various solvents like DMSO, chloroform, and methanol is crucial for its application in synthesis and research.
NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated manufacturer in China, ensures the high purity of Dasabuvir (ABT-333) through meticulous production and quality control processes. The synthesis of this compound often involves palladium-catalyzed cross-coupling reactions, utilizing specific raw materials such as 1-(3-tert-Butyl-5-iodo-4-Methoxyphenyl)pyriMidin-2,4(1H,3H)-dione and N-(6-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-naphthalen-2-yl)MethanesulfonaMide. Understanding these synthesis pathways is key for any pharmaceutical company looking to integrate this intermediate into their production lines.
When handling Dasabuvir (ABT-333), it is important to be aware of its properties. The safety data indicates it can cause skin irritation (H315) and serious eye irritation (H319), necessitating the use of appropriate personal protective equipment. As a reliable supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. provides comprehensive documentation, including safety data sheets, to ensure proper handling and storage. This attention to detail in chemical characterization and safety protocols is fundamental to our role in supporting pharmaceutical research and production, allowing clients to confidently buy and utilize this important compound.
Perspectives & Insights
Silicon Analyst 88
“Its solubility in various solvents like DMSO, chloroform, and methanol is crucial for its application in synthesis and research.”
Quantum Seeker Pro
“, as a dedicated manufacturer in China, ensures the high purity of Dasabuvir (ABT-333) through meticulous production and quality control processes.”
Bio Reader 7
“The synthesis of this compound often involves palladium-catalyzed cross-coupling reactions, utilizing specific raw materials such as 1-(3-tert-Butyl-5-iodo-4-Methoxyphenyl)pyriMidin-2,4(1H,3H)-dione and N-(6-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-naphthalen-2-yl)MethanesulfonaMide.”