In the realm of chemical synthesis, understanding the intrinsic properties of a compound is the key to unlocking its full potential. 2-Phenylisonicotinic Acid (CAS: 55240-51-2) is a critical intermediate in the pharmaceutical industry, and a thorough grasp of its chemical properties is essential for successful application. NINGBO INNO PHARMCHEM CO.,LTD. provides this vital compound and insights into its characteristics.

The fundamental chemical properties of 2-Phenylisonicotinic Acid are defined by its molecular structure: C12H9NO2, with a molecular weight of 199.21 g/mol. It is characterized by a pyridine ring substituted at the 2-position with a phenyl group and at the 4-position with a carboxylic acid group. This arrangement dictates its reactivity. The carboxylic acid group can undergo typical reactions such as esterification, amidation, and salt formation. The pyridine ring, with its nitrogen atom, can act as a Lewis base and participate in reactions characteristic of heterocycles. The phenyl group offers sites for electrophilic aromatic substitution under appropriate conditions.

Physically, 2-Phenylisonicotinic Acid typically presents as a solid, with a reported melting point in the range of 270-271°C. This high melting point indicates strong intermolecular forces, likely due to hydrogen bonding between carboxylic acid groups and potential pi-pi stacking interactions. The compound is generally stable under recommended storage conditions, which often involve keeping it in a cool, dry place in a tightly sealed container, protected from light and moisture. These handling considerations are vital for maintaining its integrity as a pharmaceutical raw intermediate.

When manufacturers decide to buy 2-phenylisonicotinic acid, they rely on detailed specifications provided by suppliers. These often include purity levels (commonly 97% min.), appearance (white to off-white solid), and solubility characteristics. Understanding its solubility in various organic solvents and water is crucial for designing reaction and purification protocols. The synthesis of 2-phenylisonicotinic acid often aims to produce the compound with minimal residual starting materials or by-products, ensuring its suitability for sensitive pharmaceutical applications.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying 2-Phenylisonicotinic Acid that meets stringent quality standards. By understanding and leveraging its chemical properties, researchers and manufacturers can effectively incorporate this key intermediate into their synthesis workflows, driving innovation in drug discovery and development.