In the realm of organic chemistry and life sciences, understanding the fundamental properties of key reagents is essential for successful research and development. NINGBO INNO PHARMCHEM CO.,LTD. provides a deep dive into Z-Val-Ala-OH, exploring its critical chemical properties and its broad spectrum of applications, particularly within peptide synthesis and pharmaceutical research.

Z-Val-Ala-OH, chemically known as N-Benzyloxycarbonyl-L-valyl-L-alanine, is a protected dipeptide derivative. Its structure incorporates the amino acids valine and alanine, linked by a peptide bond, with the N-terminus protected by a benzyloxycarbonyl (Z) group. This specific protection strategy is crucial in peptide synthesis, as it allows for controlled coupling reactions and prevents unwanted side reactions. The Z-group can be readily removed under specific conditions, typically hydrogenolysis, to reveal the free amine for further chain elongation. This controlled reactivity is a hallmark of high-quality Z-Val-Ala-OH.

The melting point of Z-Val-Ala-OH is approximately 165°C, and it typically presents as a white to off-white solid. Its density is around 1.201 g/cm³. These physical properties are important for handling, storage, and formulating the compound. Furthermore, its pKa value, predicted to be around 3.49, influences its behavior in solution and its potential interactions with other molecules. The optical activity, measured at -23.134° in ethanol, indicates its chiral nature, a critical aspect for biological applications where stereochemistry dictates function.

The applications of Z-Val-Ala-OH are diverse and impactful. Primarily, it serves as a vital intermediate in solid-phase and solution-phase peptide synthesis, enabling the creation of peptides with specific sequences and functions. These synthesized peptides find applications in drug discovery, as therapeutic agents themselves, or as research tools to probe biological pathways. NINGBO INNO PHARMCHEM CO.,LTD. supplies Z-Val-Ala-OH to researchers and companies engaged in these advanced fields, understanding the need for precise chemical characteristics.

Beyond peptide synthesis, Z-Val-Ala-OH has been utilized in the preparation and evaluation of peptide amide conjugates of nucleosides, which function as prodrugs. It also plays a role in the synthesis and evaluation of diacylhydrazines as inhibitors of enzymes like interleukin-1β converting enzyme. The ability to reliably buy Z-Val-Ala-OH from reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures that researchers can consistently implement these complex chemical strategies.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing detailed information on the chemical properties of Z-Val-Ala-OH, supporting scientific innovation. Our dedication to quality ensures that you receive a product that perfectly fits the demanding requirements of modern chemical research.