Understanding the precise chemical properties of a compound is fundamental to its effective utilization in scientific research and industrial applications. 2,4-diamino-6-hydroxypyrimidine (CAS 56-06-4) is a compound with a well-defined set of characteristics that make it a valuable asset in various fields, particularly in biochemical studies and organic synthesis.

Physically, 2,4-diamino-6-hydroxypyrimidine presents as a white to off-white crystalline powder. Its chemical formula is C4H6N4O, with a molecular weight of approximately 126.12 g/mol. A key property noted is its melting point, which occurs at a high temperature of 285-286 °C with decomposition, indicating significant thermal stability under standard laboratory conditions. Its solubility profile is also noteworthy; it is soluble in DMSO and methanol, and sparingly soluble in water, though specific concentrations in buffers like PBS are also documented.

The primary research application of 2,4-diamino-6-hydroxypyrimidine stems from its biological activity as a selective inhibitor of GTP cyclohydrolase I. This enzyme is crucial for the biosynthesis of tetrahydrobiopterin (BH4), a cofactor essential for enzymes involved in nitric oxide (NO) synthesis and the metabolism of aromatic amino acids. By inhibiting this pathway, researchers can investigate the consequences of BH4 deficiency and gain insights into cellular signaling and metabolic regulation. The compound's role in blocking NO production has made it a subject of study in various physiological and pathological contexts.

For researchers looking to purchase 2,4-diamino-6-hydroxypyrimidine, attention to purity is paramount. High purity ensures the accuracy of experimental results. The price point for this chemical intermediate reflects its specialized nature and the rigorous quality control processes involved in its production. The ability to buy 2,4-diamino-6-hydroxypyrimidine from trusted sources facilitates uninterrupted research progress.

In summary, the defined chemical properties and established biological inhibitory activity of 2,4-diamino-6-hydroxypyrimidine make it an indispensable tool for scientists exploring complex biochemical pathways. Its reliable synthesis and availability empower groundbreaking research in areas impacting human health and disease.