Understanding the chemical properties and synthesis of key reagents is fundamental to their effective utilization in research and industry. NINGBO INNO PHARMCHEM CO.,LTD. provides insight into (2-Carboxyethyl)triphenylphosphonium Bromide (CAS: 51114-94-4), a compound notable for its distinct chemical profile and accessible preparation methods.

The molecular formula of (2-Carboxyethyl)triphenylphosphonium Bromide is C21H20BrO2P, with a molecular weight of approximately 415.27 g/mol. Its exact mass is calculated at 414.038422. The presence of the triphenylphosphine moiety confers significant stability, while the carboxyethyl group introduces polarity and a site for further chemical modification. This combination of features makes it a highly sought-after intermediate in organic synthesis.

Several synthesis routes are commonly employed to produce this compound. A prevalent method involves the reaction of triphenylphosphine with 3-bromopropionic acid in a suitable solvent, often acetonitrile. This reaction, typically carried out under reflux conditions for an extended period, leads to the formation of the phosphonium salt. Post-reaction purification often involves filtration, washing with ethereal solvents, and sometimes recrystallization to achieve high purity. Researchers looking to purchase this compound can rely on NINGBO INNO PHARMCHEM CO.,LTD. for consistent quality.

Another synthetic approach might involve reacting triphenylphosphine with ω-chloropropionic acid. The choice of solvent, reaction temperature, and duration are critical parameters that influence the yield and purity of the final product. Details regarding these synthesis pathways are often found in chemical literature and are essential for chemists aiming to synthesize or understand the origins of this valuable reagent.

The physical properties of (2-Carboxyethyl)triphenylphosphonium Bromide are also noteworthy. It typically appears as a white to off-white solid, often in powder or crystalline form. Its melting point is generally reported in the range of 195-199 °C, indicating a stable solid structure. These characteristics are important for handling, storage, and application in various chemical processes.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing the scientific community with access to well-characterized and high-purity chemical compounds. By offering (2-Carboxyethyl)triphenylphosphonium Bromide, we facilitate efficient and reliable synthetic endeavors, supporting advancements in pharmaceutical development, materials science, and beyond. Our focus on quality ensures that our clients receive a product that meets their rigorous demands.