2-Chloropyrimidine (CAS 1722-12-9) is more than just a chemical compound; it's a versatile tool for innovation in chemistry and pharmaceuticals. NINGBO INNO PHARMCHEM CO.,LTD. provides insights into its fundamental characteristics and diverse applications, highlighting why it's a sought-after reagent.

With a molecular formula of C4H3ClN2 and a molecular weight of 114.53, 2-Chloropyrimidine typically appears as a white to off-white crystalline powder. Its melting point ranges from 63-66 °C, and it has a boiling point of 75-76 °C/10 mmHg. These properties, along with its slight solubility in water and good solubility in alcohol, make it manageable for various laboratory procedures. The careful handling and storage, often under argon at 2-8°C, ensure its stability and efficacy for intended uses.

The primary utility of 2-Chloropyrimidine lies in its role as a key intermediate in the synthesis of buspirone. This process involves reacting 1-(2-pyrimidinyl)piperazine with a suitable derivative that incorporates the butyl chain and the spirocyclic dione structure, with 2-Chloropyrimidine acting as the crucial pyrimidine source. Researchers focusing on pharmaceutical R&D often rely on this compound for its predictable reactivity in building complex molecular architectures.

As a chemical reagent, 2-Chloropyrimidine is instrumental in various organic synthesis reactions. Its chlorine atom can be readily displaced in nucleophilic substitution reactions, allowing for the introduction of different functional groups onto the pyrimidine ring. This versatility makes it a valuable component for chemists developing new synthetic methodologies or creating novel compounds with potential biological activity. Understanding the core 2-Chloropyrimidine synthesis pathways is beneficial for optimization.

NINGBO INNO PHARMCHEM CO.,LTD. understands the importance of reliable sourcing for critical chemical intermediates. We empower researchers and manufacturers to buy and purchase 2-Chloropyrimidine, ensuring consistent quality and availability. As a leading supplier in China, we are committed to providing competitive price points and efficient delivery, supporting your projects from early-stage research to commercial production. For those looking to acquire this essential compound, identifying reputable manufacturers is a key step.

Whether your focus is on the meticulous synthesis of pharmaceuticals like buspirone or the exploration of new frontiers in organic chemistry, 2-Chloropyrimidine is a compound that merits attention. Its precise chemical characteristics and broad applicability solidify its position as a cornerstone reagent in modern chemical laboratories and industrial processes.