Understanding the Chemical Landscape: Properties and Applications of (2S,3aR,7aS)-Octahydro-1H-indole-2-carboxylic Acid Hydrochloride
In the dynamic field of chemistry, understanding the intricate properties and diverse applications of specific molecules is key to driving innovation. (2S,3aR,7aS)-Octahydro-1H-indole-2-carboxylic acid hydrochloride is one such molecule, holding significant importance as a pharmaceutical intermediate, most notably in the synthesis of Trandolapril. NINGBO INNO PHARMCHEM CO.,LTD. offers a comprehensive understanding of this compound, from its detailed chemical characteristics to its crucial applications in drug manufacturing.
Chemically, this compound is defined by its bicyclic structure, featuring a fused pyrrolidine and cyclohexane ring system, with a carboxylic acid group positioned stereospecifically. Its molecular formula is C9H16ClNO2, and it typically presents as a white to off-white crystalline powder. The hydrochloride salt form enhances its stability and solubility, facilitating its handling and use in subsequent synthetic steps. The meticulous control required in its synthesis of (2S,3aR,7aS)-octahydro-1H-indole-2-carboxylic acid hydrochloride is a testament to its complex nature.
The primary application of this compound is as a crucial intermediate in the trandolapril intermediate synthesis. Trandolapril, an ACE inhibitor, is vital for managing hypertension and other cardiovascular conditions. The stereochemical accuracy of the intermediate is directly correlated with the biological activity of the final drug. This reliance on precise stereochemistry highlights the importance of chiral synthesis techniques and rigorous pharmaceutical intermediate quality control.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-purity (2S,3aR,7aS)-Octahydro-1H-indole-2-carboxylic acid hydrochloride that meets the stringent requirements of the pharmaceutical industry. Our expertise in advanced synthesis and analytical methods, including detailed HPLC analysis of stereoisomers, ensures that our product serves as a reliable foundation for the production of critical medications. We aim to contribute to advancements in chemical synthesis and pharmaceutical development by delivering intermediates of exceptional quality and consistency.
Perspectives & Insights
Alpha Spark Labs
“Trandolapril, an ACE inhibitor, is vital for managing hypertension and other cardiovascular conditions.”
Future Pioneer 88
“The stereochemical accuracy of the intermediate is directly correlated with the biological activity of the final drug.”
Core Explorer Pro
“This reliance on precise stereochemistry highlights the importance of chiral synthesis techniques and rigorous pharmaceutical intermediate quality control.”