Understanding the Chemical Properties and Handling of (R)-(-)-3-Quinuclidinol
The effective utilization of any chemical intermediate hinges on a thorough understanding of its properties and appropriate handling procedures. (R)-(-)-3-Quinuclidinol, chemically known as (3R)-1-azabicyclo[2.2.2]octan-3-ol and bearing the CAS number 25333-42-0, is a prime example. This compound, often appearing as a white to beige powder, possesses a molecular formula of C7H13NO and a molecular weight of 127.18 g/mol. Its physical and chemical characteristics are crucial for its role as a key pharmaceutical intermediate.
Key physical properties such as density (approximately 1.13 g/cm³), melting point (217-224°C), and boiling point (around 206.9°C at 760 mmHg, though often described with reference to reduced pressure boiling points) provide essential data for process engineers and chemists. The flash point, recorded at 97.7 ± 21.3°C, offers critical information regarding its flammability and the safety precautions required during its handling and storage.
The purity of (R)-(-)-3-Quinuclidinol is a paramount concern for pharmaceutical applications. With a specification typically set at ≥99.0%, and a loss on drying limit of ≤0.5%, manufacturers can be assured of a consistent and reliable product. This high purity minimizes the risk of unwanted side reactions during complex synthesis pathways and ensures the quality of the final active pharmaceutical ingredient (API). For those looking to buy (R)-(-)-3-Quinuclidinol, these purity metrics are key indicators of supplier quality.
Proper storage and handling are critical to maintain the integrity and efficacy of (R)-(-)-3-Quinuclidinol. It is generally recommended to store the compound in a tightly closed container, in a cool, dry, and well-ventilated area, away from incompatible substances. This precaution helps prevent degradation due to moisture or air exposure, thereby preserving its chemical stability. Packaging often involves 25kg cardboard drums, though customer-specific requirements can be accommodated, reflecting its industrial scale usage.
Manufacturers and researchers sourcing this compound often seek a dependable (3R)-1-azabicyclo[2.2.2]octan-3-ol supplier, with many turning to established producers in regions like China. Companies such as NINGBO INNO PHARMCHEM CO.,LTD. specialize in providing high-grade chemical intermediates, adhering to strict quality control measures and offering robust supply chain solutions. Their commitment to quality ensures that clients receive products that meet exacting standards for pharmaceutical synthesis, including critical intermediates like (R)-(-)-3-Quinuclidinol.
In conclusion, a comprehensive understanding of the chemical properties, purity standards, and handling guidelines for (R)-(-)-3-Quinuclidinol is fundamental for its successful application in drug development. By prioritizing quality and following recommended storage practices, researchers and manufacturers can effectively leverage this vital synthon to advance their pharmaceutical projects.
Perspectives & Insights
Agile Reader One
“By prioritizing quality and following recommended storage practices, researchers and manufacturers can effectively leverage this vital synthon to advance their pharmaceutical projects.”
Logic Vision Labs
“The effective utilization of any chemical intermediate hinges on a thorough understanding of its properties and appropriate handling procedures.”
Molecule Origin 88
“This compound, often appearing as a white to beige powder, possesses a molecular formula of C7H13NO and a molecular weight of 127.”