The Chemical Properties and Synthesis Applications of N-Boc-N'-nitro-L-arginine (CAS 2188-18-3)
N-Boc-N'-nitro-L-arginine, identified by its CAS number 2188-18-3, is a compound of considerable interest within the chemical synthesis and biochemical research communities. Possessing a distinct molecular formula (C11H21N5O6) and a molecular weight of 319.31, this white crystal powder exhibits specific chemical properties that make it a valuable asset for various applications. Its utility as a synthesis intermediate and its role in biochemical studies warrant a closer examination.
In the field of organic synthesis, N-Boc-N'-nitro-L-arginine serves as a sophisticated building block. The N-terminal Boc protecting group allows for controlled peptide coupling reactions, preventing unwanted side reactions during the synthesis of peptides or complex organic molecules. The nitro group on the guanidine side chain adds another layer of chemical functionality that can be manipulated or utilized in specific synthetic strategies. This makes it a key component for chemists aiming to construct precise molecular architectures, supporting endeavors in chiral organic synthesis and the broader chemical industry.
The compound's physical characteristics, such as its melting point ranging from 111-113 °C, and its typical appearance as a white powder, are essential data points for quality control and handling. Its solubility in common organic solvents is also a critical factor for researchers when planning experimental procedures. For those looking to purchase N-Boc-N'-nitro-L-arginine, understanding these properties ensures that the material is suitable for their intended synthesis pathway.
Beyond its synthetic applications, N-Boc-N'-nitro-L-arginine is recognized for its significant biochemical relevance, particularly as an inhibitor of nitric oxide synthase (NOS) enzymes. This inhibitory action is crucial for studying the intricate signaling cascades involving nitric oxide (NO) in biological systems. By blocking NOS activity, researchers can gain critical insights into cellular processes, disease mechanisms, and potential therapeutic targets, contributing to advancements in pharmaceutical exploration and drug development.
The availability of high-purity N-Boc-N'-nitro-L-arginine from specialized suppliers is fundamental for ensuring the reliability and reproducibility of research outcomes. Whether used in the meticulous process of peptide synthesis or in detailed biochemical investigations, this compound provides researchers with a dependable tool. Its multifaceted nature underscores its importance as a versatile chemical intermediate and research chemical.
Perspectives & Insights
Logic Thinker AI
“Its multifaceted nature underscores its importance as a versatile chemical intermediate and research chemical.”
Molecule Spark 2025
“N-Boc-N'-nitro-L-arginine, identified by its CAS number 2188-18-3, is a compound of considerable interest within the chemical synthesis and biochemical research communities.”
Alpha Pioneer 01
“Possessing a distinct molecular formula (C11H21N5O6) and a molecular weight of 319.”