3-Bromo-2-hydroxypyridine (CAS 13466-43-8) is a compound that plays a pivotal role in various chemical synthesis pathways, particularly within the pharmaceutical industry. Its unique structure, featuring a brominated and hydroxylated pyridine ring, makes it a versatile intermediate for constructing complex organic molecules.

The synthesis of 3-Bromo-2-hydroxypyridine typically involves established chemical reactions. One common route starts with 2-amino-3-bromopyridine, which undergoes diazotization followed by hydrolysis. Another method involves the direct bromination of 2-hydroxypyridine. The efficiency and yield of these processes are critical for commercial viability. Researchers often refine these chemical synthesis techniques to optimize product purity and reduce production costs.

The primary application of 3-Bromo-2-hydroxypyridine lies in its use as a key building block in medicinal chemistry. It is instrumental in the synthesis of pyrazolopyridines, a class of compounds that have shown promise as $\gamma$-secretase modulators. These modulators are of significant interest in the development of treatments for various diseases, including Alzheimer's disease.

Beyond its role in specific drug development pathways, 3-Bromo-2-hydroxypyridine serves as a general intermediate in heterocyclic chemistry. Its reactivity allows for further functionalization, enabling chemists to create a broad spectrum of novel compounds with potential applications in materials science, agrochemicals, and other fine chemical sectors. The availability of this chemical building block from reliable suppliers, such as NINGBO INNO PHARMCHEM CO.,LTD., is crucial for researchers exploring new frontiers in organic chemistry.

When considering the purchase of this compound, understanding its properties and common applications is essential. Its stability under normal conditions and its solubility in common organic solvents contribute to its ease of use in laboratory settings and industrial processes. For those looking to buy 3-Bromo-2-hydroxypyridine, partnering with experienced manufacturers ensures access to detailed technical data and consistent product quality.

In essence, 3-Bromo-2-hydroxypyridine (CAS 13466-43-8) is a testament to the importance of specialized intermediates in driving scientific advancement. Its well-defined synthesis pathways and critical applications in pharmaceutical and organic synthesis underscore its value in the chemical marketplace.