Exploring the Chemical Synthesis and Applications of 7-(4-Chlorobutoxy)-3,4-Dihydro-2(1H)-Quinolinone
The field of organic chemistry is rich with compounds that serve as vital building blocks for complex and essential molecules. Among these, 7-(4-Chlorobutoxy)-3,4-Dihydro-2(1H)-Quinolinone (CAS 120004-79-7) has emerged as a compound of significant interest, particularly within the pharmaceutical sector. Its unique chemical structure and reactivity make it an indispensable intermediate for various synthetic processes, most notably in the creation of antipsychotic drugs like Aripiprazole.
The synthesis of 7-(4-Chlorobutoxy)-3,4-Dihydro-2(1H)-Quinolinone typically involves the reaction between 1-Bromo-4-chlorobutane and 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone. This process, when executed under controlled conditions, yields a high-quality product essential for subsequent pharmaceutical manufacturing. The efficiency of this reaction pathway contributes to the compound's status as a key intermediate for those seeking to buy 7-(4-Chlorobutoxy)-3,4-Dihydro-2(1H)-Quinolinone for their production needs.
One of the primary applications of this chemical is in the aripiprazole synthesis. Aripiprazole, a crucial medication for mental health conditions, requires precise chemical precursors to ensure its efficacy and safety. The incorporation of the 7-(4-Chlorobutoxy)-3,4-Dihydro-2(1H)-Quinolinone moiety into the Aripiprazole molecule is a critical step in its manufacturing. This makes the compound highly sought after by companies involved in pharmaceutical intermediate manufacturing.
Beyond its role in Aripiprazole, this compound is exceptionally useful for the synthesis of piperazine derivatives. Piperazine rings are common structural motifs in many pharmaceuticals, offering a versatile scaffold for drug design. The ability to readily synthesize these derivatives using intermediates like 7-(4-Chlorobutoxy)-3,4-Dihydro-2(1H)-Quinolinone accelerates research and development in areas targeting the central nervous system and other therapeutic fields. Searches for 'pharmaceutical intermediate for antipsychotics' often include this compound due to its proven efficacy.
The compound's reactivity also lends itself to the production of other complex heterocyclic compounds, such as 1,5,6,8-tetrahydropyrimidines and benzimidazoles. These structures are prevalent in a wide range of biologically active molecules. The high yield pharmaceutical intermediate characteristic of 7-(4-Chlorobutoxy)-3,4-Dihydro-2(1H)-Quinolinone makes it an economically viable choice for large-scale production, supporting the goals of efficient API production chemicals.
Furthermore, its capacity for acetylating phenols and amines highlights its broader utility in fine chemical applications. This makes it a valuable reagent for chemists engaged in creating diverse organic molecules. The compound's specific chemical properties and its use in reactions like acetylation are often points of interest for those in the fine chemical building blocks sector.
In essence, 7-(4-Chlorobutoxy)-3,4-Dihydro-2(1H)-Quinolinone is a critical link in the chain of pharmaceutical innovation. Its established role in producing essential medicines and its potential for creating new therapeutic agents underscore its importance. For companies looking to secure a reliable supply, understanding the compound's synthesis, applications, and the landscape of custom pharmaceutical synthesis providers is key.
Perspectives & Insights
Core Pioneer 24
“The incorporation of the 7-(4-Chlorobutoxy)-3,4-Dihydro-2(1H)-Quinolinone moiety into the Aripiprazole molecule is a critical step in its manufacturing.”
Silicon Explorer X
“This makes the compound highly sought after by companies involved in pharmaceutical intermediate manufacturing.”
Quantum Catalyst AI
“Beyond its role in Aripiprazole, this compound is exceptionally useful for the synthesis of piperazine derivatives.”