Understanding the fundamental properties of chemical intermediates is crucial for their effective utilization in various scientific and industrial applications. 3-Pyridinesulfonic Acid, identified by CAS number 636-73-7, is a compound that offers a fascinating blend of chemical characteristics and broad applicability, particularly within the pharmaceutical sector.

Physically, 3-Pyridinesulfonic Acid presents as a white to almost white crystalline powder. Its high melting point, often cited as exceeding 300°C, indicates a robust and stable molecular structure. This stability is a key attribute for a compound intended for use in multi-step synthesis processes, where it must withstand various reaction conditions without degradation. The compound is soluble in water, a property that facilitates its handling and use in aqueous reaction media, common in many chemical synthesis workflows.

From a chemical perspective, 3-Pyridinesulfonic Acid is characterized by its pyridine ring substituted with a sulfonic acid group at the 3-position. This functionalization imparts specific reactivity patterns that are highly valuable in organic synthesis. The sulfonic acid group, being strongly acidic (pKa of -2.30 ± 0.18, predicted), can participate in various acid-catalyzed reactions or be converted into other functional groups, such as sulfonyl chlorides or sulfonamides. These derived compounds, in turn, serve as intermediates for an even wider range of chemical products.

The primary application driving the demand for 3-Pyridinesulfonic Acid is its role as a critical pharmaceutical intermediate. It is notably used in the synthesis pathway for Vonoprazan Fumarate, a proton pump inhibitor that has gained significant traction in treating acid-related gastrointestinal disorders. The precise synthesis of this API relies on the predictable reactivity and high purity of 3-Pyridinesulfonic Acid, making it an indispensable component in its manufacturing process. This underscores the importance of sourcing high-quality CAS 636-73-7 chemical properties and reliable suppliers.

Beyond pharmaceuticals, 3-Pyridinesulfonic Acid finds utility in general organic synthesis. Its pyridine ring offers a scaffold for further chemical modifications, and the sulfonic acid group provides a handle for diverse reactions. This makes it a versatile tool for researchers exploring new molecular structures, developing novel catalysts, or creating specialized chemical reagents. The demand for such reliable chemical building blocks is a testament to its broad applicability.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-purity 3-Pyridinesulfonic Acid, ensuring that our clients in the pharmaceutical and chemical research sectors have access to a reliable source for their critical synthesis needs. Our focus on quality and consistency supports the advancement of scientific discovery and the production of essential medicines.

In summary, the detailed chemical properties of 3-Pyridinesulfonic Acid, including its physical form, high melting point, solubility, and characteristic reactivity, make it an exceptionally useful compound. Its established role in Vonoprazan Fumarate intermediate synthesis and its potential in broader organic synthesis applications highlight its importance in the modern chemical landscape.