Scientific and medical breakthroughs often hinge on the availability of precise chemical building blocks that enable complex synthesis and targeted therapeutic development. 4-Chloro-3-pyridinesulfonamide, identified by its CAS number 33263-43-3, is one such compound that plays a crucial role in driving innovation, particularly within the pharmaceutical sector. This article will delve into its essential applications and the chemical characteristics that make it a cornerstone for various advanced syntheses, as facilitated by NINGBO INNO PHARMCHEM CO.,LTD.

The compound 4-Chloro-3-pyridinesulfonamide is characterized by its specific chemical structure, featuring a pyridine ring substituted with a chlorine atom and a sulfonamide group. This molecular arrangement imparts a unique reactivity that is highly valued in organic synthesis. Typically supplied as an off-white to light beige powder with a high purity of 98% or more, it is a reliable starting material for sensitive chemical reactions. Its melting point between 150-155°C signifies its stability under typical laboratory and industrial conditions. The molecular formula C5H5ClN2O2S and molecular weight of 192.62 further define its identity as a precise chemical entity, crucial for accurate synthesis planning.

A significant application of 4-Chloro-3-pyridinesulfonamide is its utility in the synthesis of pyridine-3-sulfonamide derivatives that act as inhibitors of carbonic anhydrase enzymes. Carbonic anhydrases are vital enzymes involved in numerous physiological processes, and their modulation is a key strategy for treating various diseases. For instance, inhibiting these enzymes can help manage conditions like glaucoma, epilepsy, and certain cancers. The ability to precisely synthesize these inhibitory derivatives depends heavily on the quality and availability of precursors like 4-Chloro-3-pyridinesulfonamide. This makes it a compound of immense interest for drug discovery and development pipelines.

Furthermore, 4-Chloro-3-pyridinesulfonamide is an essential component in the production of Cefozopran, a potent third-generation cephalosporin antibiotic. Antibiotics are critical for combating bacterial infections, and the continuous development of effective agents is a priority in global health. The synthesis of Cefozopran relies on this pyridine derivative to form its core structure, thereby enabling its broad-spectrum antibacterial activity. The ability to purchase this intermediate reliably from a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures that the production of this vital antibiotic can continue uninterrupted.

NINGBO INNO PHARMCHEM CO.,LTD. recognizes the importance of high-quality chemical intermediates in driving scientific progress. We are committed to providing 4-Chloro-3-pyridinesulfonamide with exceptional purity and consistency, supporting researchers and manufacturers in their endeavors. The demand for advanced chemical synthesis and the development of new therapeutics means that compounds like 4-Chloro-3-pyridinesulfonamide will continue to be critical. We are a trusted manufacturer and supplier, ensuring that these essential building blocks are accessible for the advancement of chemical and pharmaceutical sciences.

In summary, 4-Chloro-3-pyridinesulfonamide is a compound that bridges fundamental chemistry with life-changing medical applications. Its role in synthesizing carbonic anhydrase inhibitors and essential antibiotics underscores its value. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying this critical intermediate, empowering the next wave of scientific and pharmaceutical breakthroughs.