The intricate world of organic chemistry constantly unveils compounds with remarkable potential to drive innovation across various industries, most notably in pharmaceuticals. 5-Bromo-7-azaindole, a chemical entity identified by its CAS number 183208-35-7, exemplifies such versatility. This white to yellow crystalline powder is not merely a chemical compound but a critical building block that underpins significant advancements, particularly in drug synthesis and life science research.

At its core, 5-Bromo-7-azaindole is a heterocyclic compound featuring a fused pyrrole and pyridine ring system, with a bromine atom positioned at the 5th position of the azaindole core. This structural configuration endows it with specific reactivity patterns that are highly sought after in complex chemical syntheses. Its molecular formula, C7H5BrN2, and molecular weight of approximately 197.03 g/mol provide precise parameters for its use in quantitative chemical reactions. The compound's melting point typically falls within the range of 176-180°C, indicating its solid state under standard laboratory conditions, which is a practical advantage for handling and storage.

The synthesis of 5-Bromo-7-azaindole, as described in chemical literature, involves multi-step organic reactions that demand careful control of reaction conditions, reagents, and purification techniques to achieve the high purity required for pharmaceutical applications. ChemicalBook details one such synthesis pathway, highlighting the importance of specific reaction parameters and purification methods, such as recrystallization from mixed solvent systems like chloroform and hexane, to obtain a pure product with a yield of approximately 77.6%. This meticulous approach to synthesis is crucial for manufacturers aiming to provide reliable 5-Bromo-7-azaindole for use as a pharmaceutical intermediate.

The applications of 5-Bromo-7-azaindole extend beyond its primary use as a precursor to cancer drugs like Veliparib. Its reactive bromine atom and the azaindole core make it a valuable scaffold for medicinal chemists exploring new molecular entities. It can be used in the research of fluorescent probes, enabling real-time observation of cellular processes, and in the development of compounds targeting neurological disorders and viral infections. The availability of this compound from suppliers in China, often with purity levels exceeding 98%, supports these diverse research initiatives. Understanding the chemistry and synthesis of 5-Bromo-7-azaindole is therefore key to unlocking its full potential in scientific discovery and therapeutic innovation.