The Chemistry of Analgesia: An In-depth Look at cis-(+)-3-Methyl-4-(phenylamino)-1-(phenylmethyl)-4-piperidinecarbonitrile
The development of effective analgesics is a complex process that hinges on the precise synthesis and application of specialized chemical compounds. Among these, cis-(+)-3-Methyl-4-(phenylamino)-1-(phenylmethyl)-4-piperidinecarbonitrile stands out as a crucial intermediate. This white to pale yellow solid, with a guaranteed purity of at least 98%, is a foundational component in the production of Fentanyl citrate and Fentanyl hydrochloride, medications widely used for severe pain management.
The chemical properties of cis-(+)-3-Methyl-4-(phenylamino)-1-(phenylmethyl)-4-piperidinecarbonitrile are central to its utility. Its molecular formula, C20H23N3, and molecular weight of 305.41672, define its structure, which is optimized for conversion into active pharmaceutical ingredients. The precise stereochemistry indicated by 'cis-(+)-' is also vital, as different isomers can possess vastly different pharmacological profiles. Understanding the synthesis of cis-(+)-3-Methyl-4-(phenylamino)-1-(phenylmethyl)-4-piperidinecarbonitrile is therefore essential for any entity involved in the opioid synthesis supply chain.
The significance of this intermediate is amplified by its role in Fentanyl hydrochloride and Fentanyl citrate production. These powerful analgesics require a reliable source of high-quality precursors to ensure consistent manufacturing outcomes. Companies involved in custom chemical synthesis often focus on producing such intermediates to meet the stringent demands of the pharmaceutical sector, highlighting the importance of consistent cis-(+)-3-Methyl-4-(phenylamino)-1-(phenylmethyl)-4-piperidinecarbonitrile purity.
Beyond its direct applications, this compound also plays a role in the broader context of pharmaceutical precursor development and regulatory compliance. The careful storage, as recommended for cis-(+)-3-Methyl-4-(phenylamino)-1-(phenylmethyl)-4-piperidinecarbonitrile, ensures its stability and efficacy. As research into pain management continues, intermediates like this remain indispensable, bridging the gap between chemical science and life-saving medical treatments.
Perspectives & Insights
Chem Catalyst Pro
“Companies involved in custom chemical synthesis often focus on producing such intermediates to meet the stringent demands of the pharmaceutical sector, highlighting the importance of consistent cis-(+)-3-Methyl-4-(phenylamino)-1-(phenylmethyl)-4-piperidinecarbonitrile purity.”
Agile Thinker 7
“Beyond its direct applications, this compound also plays a role in the broader context of pharmaceutical precursor development and regulatory compliance.”
Logic Spark 24
“The careful storage, as recommended for cis-(+)-3-Methyl-4-(phenylamino)-1-(phenylmethyl)-4-piperidinecarbonitrile, ensures its stability and efficacy.”