4-Aminobenzoic Acid, often abbreviated as PABA, is an organic compound with the chemical formula C7H7NO2. It is a bifunctional molecule, featuring both an amino group (-NH2) and a carboxyl group (-COOH) attached to a benzene ring in para positions. This specific arrangement of functional groups gives PABA its characteristic properties and reactivity, making it a valuable intermediate in various chemical syntheses.

Physically, PABA presents as white or pale yellow crystalline powder. It exhibits limited solubility in water but is soluble in hot water, ethanol, ether, and ethyl acetate. Its melting point typically falls between 187-189 °C. The compound is known to be light-sensitive, tending to turn yellow upon exposure to air or light, which necessitates proper storage conditions to maintain its quality.

The industrial production of 4-Aminobenzoic Acid is primarily achieved through two main synthetic routes. One common method involves the reduction of 4-nitrobenzoic acid. This process typically uses reducing agents like hydrogen gas in the presence of a catalyst, or chemical reducing agents, to convert the nitro group to an amino group. Another established route is the Hoffman degradation of the monoamide derived from terephthalic acid.

These synthesis pathways are critical for providing the large quantities of PABA required by various industries. The choice of method often depends on factors such as cost-effectiveness, available raw materials, and desired purity levels. Pharmaceutical applications, for instance, demand high-purity PABA, often requiring additional purification steps after the initial synthesis.

The ability to synthesize PABA efficiently and with high purity is fundamental to its widespread use. As a key intermediate, its reliable supply underpins the production of essential pharmaceuticals, cosmetic ingredients, and other chemical products. Understanding the underlying benzoic acid, 4-amino synthesis processes allows industries to harness the full potential of this versatile molecule.

Ningbo Inno Pharmchem Co., Ltd. is a leading supplier of high-quality chemical intermediates, including 4-Aminobenzoic Acid. We leverage advanced synthesis and purification techniques to ensure our products meet rigorous industry standards. Our commitment to chemical excellence supports clients in their manufacturing processes, providing them with the essential building blocks they need for innovation and production. Partner with us for your chemical sourcing needs and benefit from our expertise in 4-aminobenzoic acid applications.