The Crucial Link: (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol as a Cornerstone in Targeted Cancer Therapy Synthesis
The relentless pursuit of more effective and less toxic treatments for cancer has led to a revolution in drug development, with targeted therapies at the forefront. These precision medicines exploit specific molecular vulnerabilities within cancer cells, often requiring highly complex and precisely engineered chemical compounds for their synthesis. Among these critical components is (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol, a pharmaceutical intermediate that plays a pivotal role in producing advanced oncology drugs.
This compound, identified by its CAS number 877397-65-4, is a key building block for Crizotinib, a prominent example of a targeted therapy approved for specific subtypes of non-small cell lung cancer (NSCLC). Crizotinib's mechanism of action involves inhibiting aberrant signaling pathways driven by genetic mutations, such as those involving the ALK gene. The precise spatial arrangement of atoms within (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol, particularly its chirality, is fundamental to Crizotinib's ability to interact with these cellular targets and exert its therapeutic effect.
The need to buy (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol arises from its indispensable role in the multistep synthesis of Crizotinib. Pharmaceutical manufacturers rely on a consistent and high-quality supply of this pharmaceutical intermediate 877397-65-4 to ensure the efficient and successful production of the final drug. The expertise involved in the synthesis of crizotinib intermediate is a significant factor in making these advanced treatments accessible to patients.
At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to supplying high-grade chiral intermediates for oncology drugs, understanding their critical importance in the pharmaceutical value chain. Our dedication to quality control and advanced manufacturing processes ensures that the dichloro-fluorophenyl ethanol uses contribute directly to the development of safer and more effective cancer treatments. The reliable sourcing of such anticancer drug intermediate synthesis components empowers researchers and drug developers to push the boundaries of medical science.
The contribution of (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol to the development of targeted cancer therapies is undeniable. By providing essential, high-purity chemical precursors, NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a partner in advancing global health and providing hope through chemical innovation.
Perspectives & Insights
Core Pioneer 24
“Crizotinib's mechanism of action involves inhibiting aberrant signaling pathways driven by genetic mutations, such as those involving the ALK gene.”
Silicon Explorer X
“The precise spatial arrangement of atoms within (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol, particularly its chirality, is fundamental to Crizotinib's ability to interact with these cellular targets and exert its therapeutic effect.”
Quantum Catalyst AI
“The need to buy (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol arises from its indispensable role in the multistep synthesis of Crizotinib.”