The efficacy of any antibiotic is largely determined by its spectrum of activity, and Cefotiam Dihydrochloride (CAS 66309-69-1) distinguishes itself with a robust performance against a diverse range of bacteria. As a third-generation cephalosporin, its antibacterial spectrum is crucial for its application in clinical settings and as a vital pharmaceutical intermediate. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. play a critical role in making this compound accessible for further pharmaceutical development.

Cefotiam Dihydrochloride exhibits significant activity against numerous Gram-negative bacteria, including species of Enterobacter, Citrobacter, and indole-positive Proteus. This broad coverage is attributed to its enhanced ability to penetrate bacterial cell membranes compared to earlier cephalosporins. Concurrently, it maintains potent activity against Gram-positive organisms, making it a versatile choice for treating mixed infections. This comprehensive coverage is what makes the purchase of Cefotiam Dihydrochloride attractive for drug developers.

The mechanism by which Cefotiam Dihydrochloride exerts its effects is by binding to and inhibiting penicillin-binding proteins (PBPs), which are essential enzymes in bacterial cell wall synthesis. By disrupting the cross-linking of peptidoglycan, the structural integrity of the bacterial cell wall is compromised, ultimately leading to cell death. This targeted approach contributes to its therapeutic success and its status as a reliable pharmaceutical intermediate.

For researchers and pharmaceutical companies, understanding the precise antibacterial spectrum and sourcing high-quality Cefotiam Dihydrochloride from reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. is essential. The price of this intermediate can vary, but its therapeutic value often justifies the investment, especially when considering its broad applications. The supply chain reliability offered by manufacturers is a key factor for consistent drug production.

In essence, the broad antibacterial spectrum of Cefotiam Dihydrochloride, coupled with its manufacturing accessibility through providers like NINGBO INNO PHARMCHEM CO.,LTD., solidifies its importance in pharmaceutical research and the treatment of bacterial infections. Its continued availability and consistent quality are vital for advancing antibacterial therapies.